Abstract
There was this metallo-enzyme known as xanthine oxidase, In the metabolism of purine nucleotides she held a special place; Hypoxanthine and xanthine she would take up with consummate ease, Oxygen and FAD she devoured, uric acid she would release. She was having a field day, her business turnover was just great, The supply of her substrates was overwhelming and never seemed to abate; Uric acid levels were mounting and soon reached a saturation point, Some of it was diverted to the renal tissue and some of it to the joints. Contrary to the generally held view that acids and water mix well, Uric acid just about manages to …
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