Unusual exuberant koilocytic proliferation in odontogenic keratocyst

Abstract

AbstractKoilocytes are characterized by peculiar histomorphologic features and are a reflection of underlying human papillomavirus (HPV) infection. Although koilocytes are present in many oral pathologies, their presence in odontogenic keratocyst (OKC) has received very little attention in the literature. When present in OKC, koilocytes are limited to the epithelial thickness and rarely involve the full thickness. In the present paper, we have reported an unusual exuberant intramural koilocytic proliferation in OKC epithelium with mild invasion into the underlying connective tissue stroma.