Abstract

Islet transplantation is emerging as an attractive alternative to solitary pancreas transplantation for a highly select group of patients with severe, labile forms of Type 1 diabetes that had previously tried and failed on intensive insulin therapy. The year 2000 marked a dramatic shift in clinical success with the introduction of the so-called ‘Edmonton Protocol’, which built upon many years of intensive research and extensive collaborations between islet groups worldwide (1,2).

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