Abstract
Unilateral magnetic resonance imaging-guided focused ultrasound pallidotomy: A novel treatment of Parkinson's disease
Highlights
Parkinson disease (PD) is a slowly progressive neurodegenerative disorder manifested by a multiple motor and non-motor symptoms
Transcranial magnetic resonance imaging-guided focused ultrasound (MRgFUS), which is a novel technique of intracranial focal ablation characterized by a minimum invasiveness, applied for several neurological and psychological disorders [3], but advanced PD [4,5]
A higher number of ultrasound rays have high incident angle with the skull on way to the target. This leads to a smaller number of elements that deliver energy effectively in MRgFUS globus pallidus internus (GPi) pallidotomy compared with ventral intermediate nucleus (Vim) thalamotomy
Summary
Parkinson disease (PD) is a slowly progressive neurodegenerative disorder manifested by a multiple motor and non-motor symptoms. Transcranial magnetic resonance imaging-guided focused ultrasound (MRgFUS), which is a novel technique of intracranial focal ablation characterized by a minimum invasiveness, applied for several neurological and psychological disorders [3], but advanced PD [4,5]. A higher number of ultrasound rays have high incident angle with the skull on way to the target. This leads to a smaller number of elements that deliver energy effectively in MRgFUS GPi pallidotomy compared with Vim thalamotomy. High SDR value is critical for the success of MRgFUS GPi pallidotomy
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