Unilateral and Bilateral Involvement of Ovarian Tumors According to Histopathological Types

Abstract

Introduction: Ovarian neoplasm is produced by the rapid growth and division of cells within the ovary. Under normal circumstances, ovarian cells reproduced to maintain tissue health. When growth control is lost and cellular division is too much and too fast, a cellular mass or tumor is formed. Ovarian neoplasm is the one of major gynecological malignancies & is a frequent site for primary & metastatic tumors. Due to its complex structure, primary ovarian neoplasm manifests a wide spectrum of clinical, morphological & histological features. Ovarian neoplasm has become increasingly important, not only because of a large variety of neoplastic entities but also because they have gradually increased the mortality rate due to genital cancer. The study aimed to find out the unilateral and bilateral involvement of ovarian tumors according to histopathological types. Methods: This cross-sectional study was carried out among forty-five patients who were admitted to the department of gynecology at Shaheed Suhrawardy Medical College & Hospital with features of ovarian neoplasm from February 2013 to February 2014. Result: A total of 45 cases were studied in this present study. Patients were of age group 2nd to 7th decade with ovarian tumors. Among 45 cases majority had benign tumors (82.3%), followed by malignant tumors (15.5%). A case of borderline tumor (2.2%) was also found. Benign tumors were the commonest in the 3rd decade. The highest frequency of malignant tumors was in the 4th to 6th decade. Germ cell tumors were found at a young age and sex cord-stromal tumor was found in the 5th decade. Most of the benign tumors (67.56%) were cystic, the rest 27.03%, and 5.42% of cases were partly cystic and partly solid respectively. Among benign tumors, two of the mature teratomas were solid. About 42.86% of malignant tumors were solid, 42.86% were partly cystic partly solid and only 14.28% cases were cystic. Among the malignant tumors, serous cystadenocarcinoma was solid in 3 out of 4 cases and the rest of the malignant tumors of different histology were partly cystic and partly solid. Borderline Brenner tumor was solid in morphology. Most of the benign cases were unilateral 78.38% and the rest 21.62% were bilateral. Among the benign cases, serous cystadenoma showed the highest percentage covering 45.95% followed by mucinous cystadenoma at 18.92%. The borderline tumor showed unilateral distribution. Among malignant cases 57.14% were bilateral and 42.86% were unilateral. Conclusion: This study concludes that benign ovarian tumors are more common from the 3rd decade & malignant tumors occur in the 4th to 6th decade. This study also showed that most of the benign tumors were cystic. Malignant ovarian tumors had an equal percentage of being solid entirely and partly cystic partly solid. Most benign cases were unilateral and malignant cases were mostly bilateral.