Abstract
Understanding the Molecular Machinery of Apoptosis
Highlights
Shaun Rosebeck* Department of Medicine, Biological Sciences Division, Hematology/Oncology Section, The University of Chicago, Chicago
Apoptosis, or Programmed Cell Death (PCD), is a critical process whose proper regulation is essential to cellular and tissue homeostasis and is frequently perturbed during the course of autoimmunity, degenerative diseases, and neoplasia
Conceptually first described in the 1800s, the cellular and histological changes associated with apoptosis were not differentiated from injurious cellular rupture until the 1960s and 1970s by seminal work from Kerr, Wyllie, and Currie
Summary
Shaun Rosebeck* Department of Medicine, Biological Sciences Division, Hematology/Oncology Section, The University of Chicago, Chicago Programmed Cell Death (PCD), is a critical process whose proper regulation is essential to cellular and tissue homeostasis and is frequently perturbed during the course of autoimmunity, degenerative diseases, and neoplasia.
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