Abstract
This review highlights the main findings on the biology of SARS CoV-2 and the strategies to combat COVID 19 pandemic. Since the initial outbreak in China on December 2019, the international scientific community joined efforts in an unprecedent public health battle. In late May 2020, 5 204 508 cases and 337 687 deaths have been reported by World Health Organization, with higher number of cases in Europe and Americas. SARS-CoV-2 was described as a novel variant from the coronavirus family and its genome was sequenced within a few months while COVID 19 quickly spread worldwide. The main cell receptor (angiotensin converting enzyme 2) was identified as involved in the invasion of host cells. As a result of the findings from cell biology, immunology and clinical studies, the pathogenesis of the virus started to be understood but it has been not fully elucidated so far. While a massive effort for the development of a vaccine is on course, preventive protocols for infection control have been proposed. Many studies on the discovering of effective therapeutic protocols have been developed, particularly on the redirection of already approved substances, but no gold standard treatment was established until now. An overview on the envisioned socioeconomic and politic impacts suggest that our society will be transformed after COVID 19 pandemia. As a result, deep changes in science, politics, socioeconomic and healthcare priorities shall appear in post-pandemia agenda.KEYWORDSCovid-19; Pandemic; SARS-CoV-2; Coronavirus. Key-words: COVID 19, pandemia, SARS-CoV-2, coronavirus.
Highlights
This review highlights the main findings on the biology of Severe Acute Respiratory Syndrome (SARS) CoV-2 and the strategies to combat COVID 19 pandemic
Several new cases of pneumonia of unknown etiology triggered the alarm for a possible new virus, similar to the causative viruses of Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS) [1,2]
Even though the first cases were detected in China, as well as the first confirmed deaths caused by the virus, on May 2020, a number of countries already have superior number of cases and deaths by COVID-19 than what has been reported in China [5]
Summary
Cristiane Yumi KOGA-ITO1, Henrique Toshiaki KOGA-ITO2, Aline da Graça SAMPAIO1, Mariana Raquel da Cruz VEGIAN1 1 - São Paulo State University (UNESP) - Institute of Science and Technology - Department of Environmental Engineering and Oral Biopathology Graduate Course – São José dos Campos – SP – Brazil. 2 - Paulista School of Medicine - Universidade Federal de São Paulo - UNIFESP.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
