Abstract
Vaccine hesitancy has become a major global public health challenge, threatening the success of vaccination programs. Despite the fact that vaccines have proven effective in fighting infectious diseases, millions of people are still hesitant to get vaccinated, especially during the pandemic. This paper identifies vaccine hesitancy in the COVID era and examines the factors that contribute to vaccine hesitancy, including a lack of trust in health institutions, misinformation, and other cognitive and demographic factors. Drawing on examples from around the world, including Africa and Brazil, this article further explores the social and political determinants that influence vaccine uptake. While Brazil has shown relatively high vaccine acceptance rates due to trust in local vaccines and the urgency of the pandemic, Africa faces great hesitation due to mistrust and misinformation. By addressing misinformation, restoring public trust and confidence in vaccines, and involving communities in the decision-making process, public health initiatives can effectively combat vaccine hesitancy and mitigate ongoing threats to global health
Published Version
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