Understanding Erythema Nodosum

Abstract

ABSTRACT Erythema nodosum is a common form of acute nodular septal panniculitis commonly found on the anterior tibial extensor surfaces. Although diagnosis is typically made based on clinical presentation, confirmation is made through biopsy that includes a portion of subcutaneous fat. Erythema nodosum is usually self-limiting, with routine treatment consisting of a conservative approach of supportive measures. Additionally, erythema nodosum is recognized as a cutaneous manifestation of systemic conditions, including inflammatory bowel disease. Dermatology providers should investigate the possibility of underlying inflammatory bowel disease and consider referral to a gastrointestinal specialist when appropriate. Therefore, the purpose of this article was to ensure providers have a thorough understanding of the diagnosis to determine appropriate treatment and identify when critical referrals are warranted. Utilizing an evidence-based, multidisciplinary approach that addresses both the gastrointestinal manifestations of inflammatory bowel disease and the cutaneous symptoms of erythema nodosum will improve both patient outcomes and satisfaction.