Abstract
To investigate dopamine reuptake sites (dopamine transporter) in the caudate nucleus and putamen in narcolepsy. Ten patients with narcolepsy and 15 controls were studied with positron emission tomography. A cocaine analogue [11C]-CFT was used as a radioligand. The uptake of[11C]-CFT was within normal limits (89% of age-adjusted control mean in the caudate nucleus and 91% in the putamen) in patients with narcolepsy. No evidence of altered striataldopamine transporter availability was found in narcolepsy.
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