Unaltered serum propranolol binding by meal-induced variations in fatty acids.

Abstract

British Journal of Clinical PharmacologyVolume 13, Issue 4 p. 575-576 Free Access Unaltered serum propranolol binding by meal-induced variations in fatty acids. CA Naranjo, CA NaranjoSearch for more papers by this authorEM Sellers, EM SellersSearch for more papers by this authorV Khouw, V KhouwSearch for more papers by this author CA Naranjo, CA NaranjoSearch for more papers by this authorEM Sellers, EM SellersSearch for more papers by this authorV Khouw, V KhouwSearch for more papers by this author First published: April 1982 https://doi.org/10.1111/j.1365-2125.1982.tb01425.xCitations: 4AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES ABEL, J.G., SELLERS, E.M., NARANJO, C.A., SHAW, J., KADAR, D. & ROMACH, M.K. (1979). Inter- and intra-subject variation in diazepam free fraction. Clin. Pharmac. Ther., 26, 247– 255. BARTER, P.J., CARROLL, K.F. & NESTEL, P.J. (1971). Diurnal fluctuations in triglyceride, free fatty acids and insulin during sucrose consumption and insulin infusion in man. J. clin. Invest., 50, 583– 591. BIRKETT, D.J., MYER, S.P. & HAGEDORN, J. (1979). Effects of fatty acids on the binding of drugs and bilirubin to human serum albumin. Advances in Pharmacology and Therapeutics, 7, 124– 134. Proceedings VII International Congress Pharmacology, Paris, 1978, Biochemical Clinical Pharmacology, ed. J.P. Tillement Oxford: Pergamon Press. BORGA, Q., PIAFSKY, K.M. & NIELSEN, O.G. (1977). Plasma protein binding of basic drugs. I. Selective displacement from α1-acid glycoprotein by tris (2-butosyethyl) phosphate. Clin. Pharmac. Ther., 22, 539– 544. DESMOND, P.V., ROBERTS, R.K., WOOD, A.J.J., DUNN, G.D., WILKINSON, G.R. & SCHENKER, S. (1980). Effect of heparin administration on plasma binding of benzodiazepines. Br. J. clin. Pharmac., 9, 171– 175. EVANS, G.H., NIES, A.S. & SHAND, D.G. (1973). The disposition of propranolol. III. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat. J. Pharmac. exp. Ther., 186, 114– 122. NARANJO, C.A., KHOUW, V. & SELLERS, E.M. (1982). Non-fatty acid modulated variations in drug binding due to heparin. Clin. Pharmac. Ther. (in press). NARANJO, C.A., SELLERS, E.M. & KHOUW, V. (1980a). Fatty acids modulation of meal-induced variations in diazepam free fraction. Br. J. clin. Pharmac., 10, 308– 310. NARANJO, C.A., SELLERS, E.M., KHOUW, V., ALEXANDER, P., FAN, T. & SHAW, J. (1980b). Variability in heparin effect on serum drug binding. Clin. Pharmac. Ther. 28, 545– 550. PATWARDHAN, R.V., DESMOND, P.V., JOHNSON, R.F., DUNN, G.D., ROBERTSON, D.H., HOYUMPA, A.M. & SCHENKER, S. (1980). Effects of caffeine on plasma free fatty acids, urinary catecholamines, and drug binding. Clin. Pharmac. Ther., 28, 398– 403. ROUTLEDGE, P.A., BJORNSSON, T.D., KITCHELL, B.B. & SHAND, D.G. (1979). Heparin administration increases plasma warfarin binding in man. Br. J. clin. Pharmac., 8, 281– 282. SAGER, G., NIELSEN, O.G. & JACOBSEN, S. (1979). Variable binding of propranolol in human serum. Biochem. Pharmac., 28, 905– 911. SCHLIERF, G. & DOROW, E. (1973). Diurnal patterns on triglycerides, free fatty acids, blood sugar, and insulin during carbohydrate-induction in man and their modification by nocturnal suppression of lipolysis. J. clin. Invest., 52, 732– 740. SELLERS, E.M., NARANJO, C.A., ABEL, J.G., KHOUW, V., SANDOR, P. & ALEXANDER, P. (1980). Fatty acid (FA) modulation of reciprocal variations in diazepam (Da) and warfarin (Wa) free fraction. Clin. Pharmac Ther., 27, 285– 286. TROUT, D.L., ESTES, E.H. & FRIEDBERG, S.T. (1960). Titration of free fatty acids of plasma: A study of current method and new modifications. J. lipid Res., 1, 199– 202. WOOD, M., SHAND, D.G. & WOOD, A.J.J. (1979). Altered drug binding due to the use of indwelling heparinized cannulas (heparin locks) for sampling. Clin. Pharmac. Ther., 25, 103– 107. Citing Literature Volume13, Issue4April 1982Pages 575-576 ReferencesRelatedInformation