Fatty acids modulation of meal-induced variations in diazepam free fraction.

Abstract

British Journal of Clinical PharmacologyVolume 10, Issue 3 p. 308-310 Free Access Fatty acids modulation of meal-induced variations in diazepam free fraction [letter] CA Naranjo, CA NaranjoSearch for more papers by this authorEM Sellers, EM SellersSearch for more papers by this authorV Khouw, V KhouwSearch for more papers by this author CA Naranjo, CA NaranjoSearch for more papers by this authorEM Sellers, EM SellersSearch for more papers by this authorV Khouw, V KhouwSearch for more papers by this author First published: September 1980 https://doi.org/10.1111/j.1365-2125.1980.tb01763.xCitations: 13AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References ABEL, J.G., SELLERS, E.M., NARANJO, C.A., SHAW, J., KADAR, D. & ROMACH, M.K. (1979). Inter and intrasubject variation in diazepam free fraction. Clin. Pharmac. Ther., 26, 247– 255. BARTER, P.J., CARROLL, K.F. & NESTEL, P.J. (1971). Diurnal fluctuations in triglyceride, free fatty acids and insulin during sucrose consumption and insulin infusion in man. J. clin. Invest., 50, 583– 591. BIRKETT, D.J., MYER, S.P. & HAGEDORN, J. (1979). Effects of fatty acids on the binding of drugs and bilirubin to human serum albumin Advances in Pharmacology and Therapeutics, 7, 124– 134, Oxford: Pergamon Press. COLBURN, W.A. & GIBALDI, M. (1978). Plasma protein binding of diazepam after a single dose of sodium oleate. J. pharm. Sci., 67, 891– 892. KLOTZ, U., ANTONIN, K.H. & BIECK, P.R. (1976). Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and rat. J. Pharmac. exp. Ther., 199, 67– 73. KLOTZ, U., ANTONIN, K.H. & BIECK, P.R. (1977). Food intake and plasma binding of diazepam. Br. J. clin. Pharmac., 4, 85– 86. KORTILLA, K. & KANGAS, L. (1977). Unchanged protein binding and the increase of serum diazepam levels after food intake. Acta Pharmac. Tox., 40, 241– 246. NARANJO, C.A., SELLERS, E.M., GILES, H.G. & ABEL, J.G. (1980). Diurnal variations in plasma diazepam concentrations associated with reciprocal changes in free fraction. Br. J. clin. Pharmac., 9, 265– 272. NARANJO, C.A., SELLERS, E.M., KHOUW, V., ALEXANDER, P., FAN, T. & SHAW, J. (1980). Identification of sources of variability in heparin effect on drug binding in human serum. Clin. Pharmac. Ther., 27, 275. SCHLIERF, G. & DOROW, E. (1973). Diurnal patterns of triglycerides, free fatty acids, blood sugar, and insulin during carbohydrate-induction in man and their modification by nocturnal suppression of lipolysis. J. clin. Invest., 52, 732– 740. SELLERS, E.M., NARANJO, C.A., ABEL, J.G., KHOUW, V., SANDOR, P. & ALEXANDER, P. (1980). Fatty acid (FA) modulation of reciprocal variations in diazepam (Dα) and warfarin free fraction (Wα). Clin. Pharmac. Ther., 27, 285– 286. SJÖDIN, T. (1977). Circular dichroism studies on the inhibiting effect of oleic acid on the binding of diazepam to human serum albumin. Biochem. Pharmac., 26, 2157– 2161. TROUT, D.L., ESTES, E.H. & FRIEDBERG, S.J. (1960). Titration of free fatty acids of plasma: a study of current method and new modification. J. Lipid Res., 1, 199– 202. TSUTSUMI, E., INABA, T., MAHON, W.A. & KALOW, W. (1975). The displacing effect of fatty acid on the binding of diazepam to human serum albumin. Biochem. Pharmac. 24, 1361– 1362. Citing Literature Volume10, Issue3September 1980Pages 308-310 ReferencesRelatedInformation