Abstract

Thirty-six years after the initial cases of what would become known as AIDS-related conditions were reported, the Human Immunodeficiency Virus (HIV) has infected over 70 million people, killed almost 35 million, and left 36.7 million People Living With HIV (PLWHIV). Realizing that, without the rapid scale-up of ART, the HIV/AIDS epidemic would continue to outrun the global response through the end of 2015, the 2014 UNAIDS “90-90-90 Fast Track Strategy” has laid the groundwork for global development strategy over the subsequent 15 years, including ending the AIDS epidemic by 2030. To accomplish this ambitious goal, the number of new global HIV infections needs to decline to less than 500,000 annually. The key to achieving the “90-90-90” strategy is the “Test and Treat” strategy adopted by the World Health Organization (WHO), but, to be successful, all HIV-positive marginalized and vulnerable populations will need to be informed, empowered, mobilized, and engaged. There are numerous challenges that realistically must be addressed and enormous barriers that need to be overcome to successfully end HIV as a global health threat. Understanding, fighting, and overcoming HIV stigma and discrimination remains one of the greatest challenges faced.

Highlights

  • The first cases of homosexual men developing opportunistic infections and cancers, Pneumocystis carinii pneumonia and Kaposi’s Sarcoma, which would come to be known as Acquired Immunodeficiency Syndrome (AIDS)-defining conditions caused by a novel retroviral infection that would soon become known as Human Immunodeficiency Virus (HIV), were reported in 1981 [1,2,3,4]

  • Almost thirty-six years later, HIV has infected more than 70 million people globally, AIDS-related conditions have killed almost 35 million people, and 36.7 million people are living with HIV (PLWHIV) [5]

  • If the HIV/AIDS epidemic is ever really going to be controlled, civil, political, economic, cultural, and Sexual and Reproductive Health and Rights (SRHR) must be addressed with significant progress made across the entire spectrum

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Summary

Introduction

The first cases of homosexual men developing opportunistic infections and cancers, Pneumocystis carinii pneumonia and Kaposi’s Sarcoma, which would come to be known as Acquired Immunodeficiency Syndrome (AIDS)-defining conditions caused by a novel retroviral infection that would soon become known as HIV, were reported in 1981 [1,2,3,4]. UNAIDS and the World Health Organization (WHO) launched the “3 by 5” Initiative in 2003 with an ambitious global target that aimed to get 3 million PLWHIV on Antiretroviral Therapy (ART) by 2005 [8].

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