Abstract
SummaryA case of Waldenstrom macroglubinemia complicated by mixed lgM-IgG cryoglobulinemia is presented.The clinical symptomatology, polymorphous and severe, could be related to physical and immunological reaction of cryoglobulin : fingers, gangrene, vascularitis, renal impairment, Gougerot-Sjogren’s syndrome.The therapeutic effect of chlorambucil was dramatic.
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