Ultrastructure of the exocrine pancreas in the snake Waglerophis merremii ( Wagler)

Abstract

Three types of serozymogenic cells were found in the secretory compartment of the snake exocrine pancreas. Type I cell was the most common and presented a well-developed granular endoplasmic reticulum arranged in cisternal and vesicular forms. The cisternal form was located predominantly in the basal regions of the cell and the vesicular form was found in the supranuclear regions of the cell next to a prominent Golgi complex. Mature secretory granules were seen at the cell apex. The cytoplasmic matrix of the Type II cells was electron dense but had only poorly-developed organelles. Secretory granules were rare. The cytoplasmic matrix of the Type III cells was electron lucent and the granular endoplasmic reticulum in the cisternal form was located predominantly in the supranuclear region, whereas the vesicular form was randomly distributed throughout the cytoplasm. The nucleus appeared pale due to the fine dispersion of the chromatin; the nucleolus was prominent. Centroacinar and intermediate cells were also examined.