Ultrastructural characterization of the accessory lobes of Lachi (Hofmann's nuclei) in the nerve cord of the chick. I. Axoglial synapses

Abstract

Light microscopic observations of the accessory lobes of Lachi of one-day-old chicks show that this tissue contains abundant amounts of glycogen and consists of cells which are similar in appearance to those of the glycogen body. Ultrastructural studies reported here for the first time confirm the presence of glycogen-rich cells in the accessory lobes and reveal that these cells are intimately associated with nerve axons. The finding of synaptic complexes and other junctional specializations between nerves and accessory lobe cells suggests that they may have a functional relationship with the nervous system. It is felt that the accessory lobe cells may be neuroglia, possibly of the astrocytic type, which have an innate capacity for glycogen storage. While the functional significance of such glycogen remains obscure, the close morphological association between neurons and the accessory lobe cells enhances the hypothesis put forth by us regarding the glycogen body, namely that neural glycogen is involved in myelin synthesis in the avian nervous system.