Abstract
The morphological changes of the abdominal aorta and inferior vena cava were studied from one to seven days following application of mild mechanical trauma (compression of the vessel wall with a clamp covered by rubber tubing). Both light microscopy of silver-stained surface preparations and electron microscopy of sectioned vessels were performed. The following morphological changes were observed in both the vena cava and abdominal aorta at all time sequences investigated: focal necrosis, abnormal overlapping of endothelial cells and pseudopod-formation from them usually directed into the lumen; and pseudopod-formation from medial smooth muscle cells, often passing into the intima via fenestrations in the elastic membrane. Leucocytes accumulated in the vessel wall only in the vena cava, whereas the ground substance increased only around myointimal cells of the aorta. The genesis and significance of the above changes are discussed.
Published Version
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