Abstract
AbstractA facile and green ultrasound‐assisted synthesis of Cu2O nanocubes at room temperature is presented. The Cu2O nanocubes were characterized using XRD, SEM, TEM, energy‐dispersive X‐ray spectroscopy, UV/Vis spectroscopy, differential scanning calorimetry with thermogravimetric analysis, and FTIR spectroscopy. The Cu2O nanocubes were employed as a heterogeneous nanocatalyst and were found to be highly active in the preparation of quinazolines by the tandem cyclization of 2‐bromobenzaldehydes with amidines under ligand‐free conditions. Various quinazolines could be prepared in excellent yields within a very short reaction time. Furthermore, the Cu2O nanocatalyst could be recycled and reused up to four times without any significant loss of catalytic activity.
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