Abstract
Encapsulation of physicochemical indicators and incorporation of FRET probes within model membrane vesicles has enabled valuable insights into membrane interactions, including pore formation, solution exchange, changes to membrane morphology and fusion dynamics. To characterize and quantify membrane interactions induced by a wide-variety of disruptive agents, including detergents and protein aggregates linked with neurodegenerative diseases, we have implemented high throughput fluorescence assays based on measuring the extent of Ca2+ entry into, and lipid mixing within, single surface-tethered vesicles.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
