Abstract
Optical glass fiber has played a key role in the development of modern optical communication and attracted the biotechnology researcher's great attention because of its properties, such as the wide bandwidth, low attenuation and superior flexibility. For ultrafast optical imaging, particularly, it has been utilized to perform MHz time-stretch imaging with diffraction-limited resolutions, which is also known as serial time-encoded amplified microscopy (STEAM). Unfortunately, time-stretch imaging with dispersive fibers has so far mostly been demonstrated at the optical communication window of 1.5 μm due to lack of efficient dispersive optical fibers operating at the shorter wavelengths, particularly at the bio-favorable window, i.e., <1.0 μm. Through fiber-optic engineering, here we demonstrate a 7.6-MHz dual-color time-stretch optical imaging at bio-favorable wavelengths of 932 nm and 466 nm. The sensitivity at such a high speed is experimentally identified in a slow data-streaming manner. To the best of our knowledge, this is the first time that all-optical time-stretch imaging at ultrahigh speed, high sensitivity and high chirping rate (>1 ns/nm) has been demonstrated at a bio-favorable wavelength window through fiber-optic engineering.
Highlights
It has become increasingly popular in recent years, extra efforts are needed to improve the reliability, portability and cost-efficiency of those bio-optical systems for their practically clinical applications
Optical glass fiber has played a key role in the development of modern optical communication and attracted the biotechnology researcher’s great attention because of its properties, such as the wide bandwidth, low attenuation and superior flexibility
It has been utilized to perform MHz time-stretch imaging with diffraction-limited resolutions, which is known as serial time-encoded amplified microscopy (STEAM)
Summary
It has become increasingly popular in recent years, extra efforts are needed to improve the reliability, portability and cost-efficiency of those bio-optical systems for their practically clinical applications. Optical glass fiber has played a key role in the development of modern optical communication and attracted the biotechnology researcher’s great attention because of its properties, such as the wide bandwidth, low attenuation and superior flexibility.
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