Abstract
71 Y chromosome-specific biallelic markers that are characteristic of major Asian haplogroups and subhaplogroups were selected. Genomic DNA was extracted from saliva samples of 202 unrelated Chinese Han male individuals in Xinjiang. Typing of 71 biallelic markers was performed using the MassARRAY MALDI-TOF MS platform (Sequenom Inc.). Allelic frequencies, gene diversities (GD) for each locus were then determined. Haplotype diversity (HD) was also calculated. Out of the 71 tested Y-chromosomal markers, five loci were not polymorphic (GD=0), 13 loci were found to be low informative (0.01<GD<0.2), 20 loci were found to be medium informative (0.2≤GD<0.3), 33 loci were found to be high informative (GD≥0.3). Of 76 observed haplotypes, 61 (80%) were unique and 15 (20%) were found more than once. The total polymorphic markers giving high haplotype diversity (0.9930) demonstrate the utility of these loci for forensic purpose.
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