Abstract
Two new nitrogen-containing compounds, pseudosteheterins A (1) and B (2), were isolated from the glycosides-enriched cardioprotective fraction of the 70% EtOH extract of the roots of Pseudostellaria heterophylla. Their structures were elucidated by spectroscopic methods, and the absolute configuration of 1 was established by quantum chemical TDDFT calculation of the ECD spectrum of its model compound. Pseudosteheterin B showed significant protective effects in H9c2 myocardial cells against CoCl2-induced injury.
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