Abstract
This report describes our experience with two cases that were ultimately diagnosed as retroperitoneal liposarcoma using endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). Case 1 is that of a 54-year-old woman with chief complaints of nausea and abdominal distention. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a large (15 cm diameter) tumor, which was significantly compressing the stomach and apparently occupied the entire left abdominal cavity. Although advanced primary gastrointestinal stromal tumor (GIST) or retroperitoneal tumor was inferred as the differential diagnosis, a definitive diagnosis was difficult using imaging alone. After EUS-FNA was done, the tumor was diagnosed histopathologically as high-grade liposarcoma. Case 2 is that of a 73-year-old man. Abdominal ultrasonography and CT showed a 6 cm diameter tumor within the pelvic cavity. The tumor had high MRI signal-intensity on both T1 and T2 images. Endorectal EUS showed a hyperechoic mass. The images suggested lipoma or liposarcoma containing lipoma-like components. Myxoid liposarcoma was revealed by subsequent EUS-FNA. Performing EUS-FNA was clinically useful for determining the subsequent therapeutic strategy in these cases where a tumor of unknown origin existed in the retroperitoneum.
Highlights
Endoscopic ultrasonography (EUS) is an important modality in the evaluati of luminal gastrointestinal diseases as well as diseases of the pancreas, gallbladder, and biliary ductal system
Liposarcoma is a malignant soft-tissue tumor that frequently occurs in extremities and retroperitoneum [3], it reportedly occurs rarely in the GI tract in locations such as the stomach, pancreas, mesenterium, and greater omentum
We report two cases in which such lesions occurred primarily in the retroperitoneum which were diagnosed as liposarcoma using Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)
Summary
Two Cases of Retroperitoneal Liposarcoma Diagnosed Using Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA).
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