Two cases of intraoperative ST segment depression treated with landiolol under combined spinal-epidural anesthesia in middle aged women

Abstract

We report two cases in which landiolol, an ultrashort-acting beta 1-selective blocker, was effective for ST segment depression observed under combined spinal-epidural anesthesia. In the first case, after administration of ephedrine for decrease in blood pressure, tachycardia and ST segment depression began to be observed during cesarean section. In the second case, following ephedrine administration for decreased blood pressure, tachycardia and ST segment depression were confirmed and the patient complained of chest pain during leiomyomectomy. In both cases, all of these symptoms were improved by administration of landiolol, and blood pressure was increased without use of a hypertensive drug.