Abstract
Guanidinopropyl end-modified poly(ethylene glycol) (Gu-PEG) with the molecular weight of 500, 2000, or 5000 has been synthesized and formed the mono-ion complex (MIC) with plasmid DNA (pDNA). The resulting MICs were locally injected into skeletal muscle in mice. By use of Gu-PEG with the molecular weight of 5,000, the resulting gene expression of pDNA was maximal. The molecular weight of PEG chain length in MICs has tuned the gene expression in skeletal muscle.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
