Tunable Fluorescence, Morphology, and Antibacterial Behaviors of Conjugated Oligomers via Host-Guest Supramolecular Self-Assembly.

Abstract

Host-guest supramolecular self-assembly has become one facile but efficient way to regulate the optical properties of conjugated oligomers and construct promising photofunctional materials. Herein, we design two linear conjugated oligomers terminated with two or four pyridinium moieties, which show different 1:1 'head-to-tail' binding patterns with cucurbit[8]uril (CB[8]) to form host-guest supramolecules. After being encapsulated in the hydrophobic cavity of the CB[8] host, the fluorescence emission of the conjugated oligomers undergoes significant changes, resulting in tunable fluorescence color with enhanced quantum yields. Triggered by the aggregation of supramolecules, the regular or rigid binding modes lead to the formation of cuboids and spheroids in nanoscale, respectively. Due to the macrocyclic-confinement effect, the light-driven reactive oxygen species (ROS) production of the host-guest complex is increased significantly, thereby improving the photodynamic antibacterial performance toward Staphylococcus aureus (S. aureus).