Abstract
Tumour markers in clinical oncology comprises substances that are produced by malignant cells or the substances that are produced by other cells under the influence of malignant cells and that can be determined in body fluids. Tumour markers can be found in cells, tissues or body fluids. These are biochemical substance. Tumour markers can be classified in according to their chemical structure, their tissue of origin, types of malignancies in which they are elevated. The concentration of tumor marker are related to the growth of malignant tumours in patients. Application of molecular tumor markers, which make histology more accurate and additionally help to prognosticate cancer. Early detection would significantly decrease the mortality rate of oral cancer. The utilization of tumour markers depends upon the sensitivity, specificity and upon reliability of methods that are being used for the same purpose. This review include different types of markers their application and limitation.
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