Clinical value of detection of tumor markers in bronchoalveolar lavage fluid and serum in the diagnosis of lung cancer

Abstract

Objective To study the value of detection of the concentration of tumor markers in the bronchoalveolar lavage fluid(BALF) and serum in the diagnosis lung cancer. Methods Fifty lung cancer patients admitted and treated in Jiyuan People’s Hospital from January 2016 to December 2017 were selected as the study group, and 50 patients with benign lung diseases were selected as the control group at the same period. The concentrations of tumor markers in BALF and serum were tested, and the test results of the two groups were analyzed. Results All of the tumor markers in the BALF and serum of the study group were higher than those of the control group, and all the tumor markers in the BALF were higher than those in the serum (P<0.05). The tumor markers in BALF of patients with different clinical stages were significantly higher than those in serum, and the differences were significant (P<0.05). The tumor markers in BALF were significantly higher than those in serum in patients with different pathological types, and the differences were significant (P<0.05). Conclusions In the diagnosis of lung cancer, the detection of tumor markers in BALF is better than that in serum, which is helpful to obtain accurate early diagnosis results and determine pathological types and prognosis of patients. Key words: Carcinoembryonic antigen; Lung cancer; Clinical diagnosis; Alveolar lavage fluid; Tumor marker