Abstract
The biometrical and biological aspects of phenotypical associations between blood groups and diseases are discussed with a brief historical reference to the work done in this field. The statistical methods for studying this subject are described in detail and the present status of knowledge of the associations between the ABO blood groups and tumors is outlined. Current hypotheses as to the biological significance of these associations are discussed with special reference to the immunological analogy hypothesis, taking into account the most recent findings on the distribution of group-specific substances in the organism.
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