Abstract
There is a general agreement between our laboratories 1 and that of Dr Tibayrenc 2 (and see Comment article, this issue) on the existence of two major phylogenetic lineages in Trypanosoma cruzi. Both groups also agree that, within each lineage, genetic diversity exists. The difference between the two research groups is the interpretation of the operational value of the two lineages. Tibayrenc’s group finds that the average and maximum genetic distances within each lineage are not much lower than those recorded in the whole species (this issue). Our data indicate molecular, biological and ecoepidemiological features that correlate to the two proposed lineages. It is interesting to note that in order to characterize the two lineages, the two groups have employed different molecular markers. Tibayrenc’s group used isoenzyme and RAPD (randomly amplified polymorphic DNA) analyses 2 . In our case, the first evidence for the two T. cruzi clusters
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call