Abstract
The major milk whey protein of ruminants is β-lactoglobulin. Ovine β-lactoglobulin-encoding gene expression is restricted to the sheep mammary gland. This report describes the expression profile of a truncated β-lactoglobulin transgene which, although not expressed in the mammary gland, is expressed in the kidney in the majority of lines generated. The high frequency of ectopic kidney expression may relate to the ability of the larger β-lactoglobulin transgenes to be expressed in a position-independent manner in the mammary gland of transgenic mice.
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