Triticones, Spirocyclic Lactams from the Fungal Plant Pathogen Drechslera tritici-repentis

Abstract

Triticones A [1], B [2], C [3], D [4], E [5], and F [6] were isolated from the culture broth of the plant pathogenic fungus Drechslera tritici-repentis(=Pyrenophoria tritici-repentis). The structures of these γ-lactams were determined by a combination of single crystal X-ray diffraction and spectroscopic analyses. A series of 2D nmr experiments has clarified the spectral assignments of triticones A [1] and B [2] and their interconversion