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https://doi.org/10.1039/b406820c
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Cite Journal: Organic & biomolecular chemistry |  Publication Date: Jan 1, 2004 |
 Citations: 15 |
Affiliation: Kobe University, Fuji Xerox (Japan)
The first synthesis of mispyric acid (1), an inhibitor of DNA polymerase beta with a novel triterpene skeleton, was achieved by starting from isoprene (2), geraniol (6) and 1,5-dimethoxy-1,4-cyclohexadiene (14). The absolute configuration of the naturally occurring 1 was determined as 2S,4S.
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