Abstract

Terpenoids form numerous and structurally diverse family of secondary metabolites derived from C5 isoprene units joined in a head-to-tail fashion. Among the terpenoids, triterpenoids emerge as a unique and large group of phytochemicals. There is secondary metabolites steroid, which is modified triterpenoids containing tetracyclic ring system but losing three methyl at C-4 and C-14. Triterpenoids and steroids can be obtained in the family Meliaceae. The Chisocheton genus which is part of the Meliaceae family is known for secondary metabolites, such as terpenoids, phenolics, and steroids. The purpose of this research is to isolate and to elucidate triterpenoids and steroid compounds from rind of Chisocheton macrophyllus. Stigmastane-type steroid Stigmast-22-en-3β-ol (1) and pentacyclic triterpenoid moronic acid (2), were isolated from the n-hexane extract of the rind of C. macrophyllus using column chromatography. The chemical structures of compounds 1-2, were identified on the basis of spectroscopic evidence and by comparison with those spectra previously.

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