Trimesic acid-modified magnetic gum as a highly efficient and recyclable biocatalyst for the one-pot green synthesis of condensation reactions

Abstract

In this work, a novel and efficient magnetic biocatalyst was designed, prepared and identified using cherry tree gum as a biopolymer functionalized with 1,3,5-benzenetricarboxylic acid (gum@Fe3O4@BTA). The obtained biocatalyst was prepared using available and cheap materials in an easy process. This biocatalyst was used as an efficient catalyst with high catalytic activity for the synthesis of a three-component one-pot protocol and four-component one-pot protocol of tetrahydro-4H-chromene derivatives and polyhydroquinoline derivatives in EtOH green solvent under reflux conditions, respectively. The synthesized heterogeneous biocatalysts were identified and analyzed by FT-IR, EDS, FESEM, TGA and XRD techniques. The synthesis of tetrahydro-4H-chromene and polyhydroquinoline derivatives by using this biocatalyst has advantages such as high efficiency, short reaction time, simple work method, absence of dangerous solvents, environmentally friendly conditions, easy separation of the biocatalyst by an external magnet, and the ability reuse for five periods without significant decrease in catalytic activity.