Triglyceride biosynthesis in the intestinal mucosa

Abstract

1. 1. The chemical type of triglyceride synthesized by the enzymes of the hamster intestinal mucosa from monoglycerides and fatty acids have been examined employing AgNO 3-impregnated silica-gel thin-layer plates. 2. 2. When 2-monopalmitin and palmityl-CoA or oleyl-CoA or the combination of the CoA thioesters of the fatty acids were employed, a close-to-theoretical distribution of the fatty acids in the synthesized triglycerides was obtained. 3. 3. When the free fatty acids and an activating system were substituted for the CoA derivatives a preferential utilization of palmitic acid was observed. 4. 4. The relationship of the reported findings to the overall absorption of triglyceride is discussed.