Abstract
Orofacial neuropathic pain happens due to somatosensory nervous system injury or disease in the orofacial region. Multiple types of orofacial neuropathic pain have been identified, including nonodontogenic neuropathic orofacial pain, postherpetic neuralgia, atypical odontalgia, glossopharyngeal neuralgia and trigeminal neuralgia. Currently, pharmacological intervention is well known as the foundation for managing neuropathic pain. Drugs from different classifications, including anticonvulsants, antidepressants, opioids, and nonsteroidal anti-inflammatory drugs, are generally used to treat these events. However, these drugs are not yet broadly accepted for these treatments. This review will explore recent clinical findings and fragments of evidence regarding anticonvulsants and antidepressants in the management of trigeminal neuralgia.
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