Abstract
A case report of a patient with severe acute trichinosis is presented. The patient was observed before, during and after a period of administration of ACTH. Clinical improvement occurred coincident with the use of ACTH and was for the most part sustained during the period following its use. Observations of the extent and character of the muscle invasion and concomitant diffuse myositis were made and are discussed. The eosinophilia so characteristic of the disease fell slowly during the administration of ACTH. Progressive rise of antibodies occurred. It is believed that distinct benefit occurred as a result of the course of ACTH. The possible mechanisms of its action in trichinosis are briefly discussed. It is suggested that ACTH be tried in future cases of trichinosis to assess further its possible beneficial role.
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