Abstract
Characterize severity of opioid use disorder during pregnancy over time. A retrospective chart review of pregnant women presenting to MetroHealth's Mother and Child Dependency program from 2002-2019 was performed. Severity of opioid use disorder was assessed by multinomial multivariable logistic regression of five discrete measures. Term birth rates and MAT use were analyzed using univariate regression. 606 women were included in this study. Duration of use, age at first use, polysubstance use, and route of administration did not significantly change over time. Significantly more women reported high use (>1 g daily) over time compared to low use (<0.5 g daily) (RRR = 1.21, p < 0.01). Buprenorphine use increased compared to methadone use (RRR = 1.54, p < 0.001). Rate of full-term delivery increased (RRR = 1.14, p < 0.001). Severity of opioid use disorder during pregnancy did not change over time. An increase in term births and preference for buprenorphine were observed.
Published Version
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