Abstract
List of contributors Preface Part I. The Clinical Problem: 1. The characterization and definition of treatment-resistant mood disorders Daniel Souery, Olivier Lipp, Isabelle Massat and Julien Mendlewicz 2. Overview of treatment-resistant depression and its management John P. O'Reardon and Jay D. Amsterdam Part II. Biological Basis: 3. Psychoneuroendocrine aspects of treatment-resistant mood disorders Owen M. Wolkowitz and Victor I. Reus 4. Estrogen and depressive illness in women Barbara B. Sherwin 5. Sleep abnormalities in treatment-resistant mood disorders Martin P. Szuba, Antonio T. Fernando and Geralyn Groh-Szuba 6. Structural and functional brain imaging in treatment-resistant depression Terence A. Ketter, Christopher J. Bench, Mark S. George, Tim A. Kimbrell and Robert M. Post 7. Immunologic factors in treatment-resistant depression Anna Sluzewska, Janusz Rybakowski, Mady Hornig and Jay D. Amsterdam Part III. Treatment Approaches: 8. Selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors in treatment-resistant depression William Boyer and Richard Bunt 9. Conventional and second generation monoamine oxidase inhibitors in treatment-resistant depression David Bakish and Cynthia L. Hooper 10. Drug combination strategies Lawrence H. Price, Linda L. Carpenter and Steven A. Rasmussen 11. Electroconvulsive therapy in medication-resistant depression Max Fink 12. Thyroid augmentation Russell T. Joffe 13. Cognitive therapy and psychosocial interventions in chronic and treatment-resistant mood disorders Jan Scott and Robert J. DeRubeis Part IV. Special Patient Populations: 14. Chronic and refractory mood disorders in childhood and adolescence Adelita Segovia, Kelly N. Botteron and Barbara Geller 15. Treatment-resistant depression in the elderly Paul A. Newhouse and Jaskaran Singh 16. Management of treatment-resistant depression during pregnancy and the postpartum period Zachary N. Stowe, Pamela McCreary, Amy Hostetter, Claudia Baugh and Alexis Llewellyn 17. Preliminary algorithms for treatment-resistant bipolar depression Robert M. Post, Mark A. Frye, Kirk D. Denicoff, Andrew M. Speer, Susan R. B. Weiss and Gabriele S. Leverich 18. Medical disorders and treatment-resistant depression John P. O'Reardon and Jay D. Amsterdam 19. Psychiatric comorbidity in treatment-resistant depression Jonathan E. Alpert and Isabelle T. Lagomasino 20. Suicide in treatment-refractory depression Jan Fawcett and Stanley G. Harris Sr Part V. Economic and Ethical Issues: 21. The economic impact of treatment non-response in major depressive disorders Jeffrey S. McCombs, Glen L. Stimmel, Rita L. Hui and T. Jeffrey White 22. Ethical issues in research and treatment of patients with mood disorders Paul Root Wolpe and Arthur Caplan Index.
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