Treatment With Vaginal Oxygen Therapy in Patients With Genitourinary Syndrome of Menopause Symptoms: An Observational Trial

Abstract

Genitourinary Syndrome of Menopause (GSM) GSM is a chronic and progressive condition that can have many medical consequences (vaginal dryness, vulvar pain, dyspareunia, and dysuria) that may affect quality of life. The objective of our study was to evaluate the efficacy of vaginal hyperbaric oxygen treatment on GSM. Thirty patients received six weekly sessions of 95% pure oxygen that was delivered at a flow of 2 lt/ minute for 15 minutes using a cannula designed for vaginal therapy, with a subsequent follow-up after two months. There was a significant improvement in vaginal dryness (before treatment VAS 7.52 versus 3.52 after treatment -p = 0.05). The same improvement was observed for vulvar burning/pain and dyspareunia, but these were not statistically significant. VHI before treatment was 15.1 versus 19.59 after treatment (p = 0.05). All the parameters maintain their value at 2 months of follow-up. No adverse effects were observed.