Abstract
Most of the physiological derangements that contribute to critical care outcome prediction models are responsive to direct therapy to correct them. For example K+ infusions for serum K+ levels; and inotropes for blood pressure changes. The total physiological score attained by a patient is therefore a product of the patient's illness and also the degree of physiological control that is achieved by critical care therapy. Differences in therapeutic culture between critical care units (and indeed the same critical care units over time) may therefore have a major influence on the final/score outcome prediction. We have assessed the percentage of patients in each score band of high abnormal range (+4), normal (0) and low abnormal range (+4) for each physiological variable for APACHE II [1] having treatment specifically targeted to correct that variable to normal, in order to define a treatment profile for our ICU.
Highlights
Intra-abdominal pressure (IAP) is an important parameter and prognostic indicator of the patient’s underlying physiologic status [1]
Smaller aerosol particles resulted in greater drug delivery in vitro when using the modified Aeroneb Pro during controlled mechanical ventilation (CMV)
We retrospectively reviewed 107 procedures performed on 48 patients in the period between March 2000 and November 2001
Summary
Intra-abdominal pressure (IAP) is an important parameter and prognostic indicator of the patient’s underlying physiologic status [1]. The aim of this study was to assess the respiratory effects of sufentanil and remifentanil in postsurgical critically ill patients during spontaneous ventilation since the drugs show pharmacokinetic and pharmacodynamic properties which make them attractive for intensive care use. Preliminary evidence suggests that hU-II levels during cardiac surgery are increased in patients with myocardial dysfunction [2] It is not known, if hU-II plasma concentrations are related to pulmonary capillary wedge pressure (PCWP) as an estimate of left ventricular filling pressure. AAF in cardiac surgery postoperative period has been implicated as a complication that leads to longer ICU and hospital stay and to augmented costs It has not been associated with increased mortality rates. We aimed to investigate the effects of use of preoperative and early postoperative standard and immunonutrient products on immune system and acute inflammatory response in the patients undergoing gastrointestinal malignancy surgery.
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