Abstract
Table of contentsP001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP effluxR. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. EllisP002 - Lower serum immunoglobulin G2 level does not predispose to severe flu.J. Solé-Violán, M. López-Rodríguez, E. Herrera-Ramos, J. Ruíz-Hernández, L. Borderías, J. Horcajada, N. González-Quevedo, O. Rajas, M. Briones, F. Rodríguez de Castro, C. Rodríguez GallegoP003 - Brain protective effects of intravenous immunoglobulin through inhibition of complement activation and apoptosis in a rat model of sepsisF. Esen, G. Orhun, P. Ergin Ozcan, E. Senturk, C. Ugur Yilmaz, N. Orhan, N. Arican, M. Kaya, M. Kucukerden, M. Giris, U. Akcan, S. Bilgic Gazioglu, E. TuzunP004 - Adenosine a1 receptor dysfunction is associated with leukopenia: A possible mechanism for sepsis-induced leukopeniaR. Riff, O. Naamani, A. DouvdevaniP005 - Analysis of neutrophil by hyper spectral imaging - A preliminary reportR. Takegawa, H. Yoshida, T. Hirose, N. Yamamoto, H. Hagiya, M. Ojima, Y. Akeda, O. Tasaki, K. Tomono, T. ShimazuP006 - Chemiluminescent intensity assessed by eaa predicts the incidence of postoperative infectious complications following gastrointestinal surgeryS. Ono, T. Kubo, S. Suda, T. Ueno, T. IkedaP007 - Serial change of c1 inhibitor in patients with sepsis – A prospective observational studyT. Hirose, H. Ogura, H. Takahashi, M. Ojima, J. Kang, Y. Nakamura, T. Kojima, T. ShimazuP008 - Comparison of bacteremia and sepsis on sepsis related biomarkersT. Ikeda, S. Suda, Y. Izutani, T. Ueno, S. OnoP009 - The changes of procalcitonin levels in critical patients with abdominal septic shock during blood purificationT. Taniguchi, M. OP010 - Validation of a new sensitive point of care device for rapid measurement of procalcitoninC. Dinter, J. Lotz, B. Eilers, C. Wissmann, R. LottP011 - Infection biomarkers in primary care patients with acute respiratory tract infections – Comparison of procalcitonin and C-reactive proteinM. M. Meili, P. S. SchuetzP012 - Do we need a lower procalcitonin cut off?H. Hawa, M. Sharshir, M. Aburageila, N. SalahuddinP013 - The predictive role of C-reactive protein and procalcitonin biomarkers in central nervous system infections with extensively drug resistant bacteriaV. Chantziara, S. Georgiou, A. Tsimogianni, P. Alexandropoulos, A. Vassi, F. Lagiou, M. Valta, G. Micha, E. Chinou, G. MichaloudisP014 - Changes in endotoxin activity assay and procalcitonin levels after direct hemoperfusion with polymyxin-b immobilized fiberA. Kodaira, T. Ikeda, S. Ono, T. Ueno, S. Suda, Y. Izutani, H. ImaizumiP015 - Diagnostic usefullness of combination biomarkers on ICU admissionM. V. De la Torre-Prados, A. Garcia-De la Torre, A. Enguix-Armada, A. Puerto-Morlan, V. Perez-Valero, A. Garcia-AlcantaraP016 - Platelet function analysis utilising the PFA-100 does not predict infection, bacteraemia, sepsis or outcome in critically ill patientsN. Bolton, J. Dudziak, S. Bonney, A. Tridente, P. NeeP017 - Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patientsG. Nicolaes, M. Wiewel, M. Schultz, K. Wildhagen, J. Horn, R. Schrijver, T. Van der Poll, C. ReutelingspergerP018 - Il-8: is this a more reliable biomarker for sepsis severity than CRP, Procalcitonin, E-selectin, IL-6 and TNF-[alpha]S. Pillai, G. Davies, G. Mills, R. Aubrey, K. Morris, P. Williams, P. EvansP019 - Relation between adrenomedullin and short-term outcome in ICU patients: Results from the frog ICU studyE. G. Gayat, J. Struck, A. Cariou, N. Deye, B. Guidet, S. Jabert, J. Launay, M. Legrand, M. Léone, M. Resche-Rigon, E. Vicaut, A. Vieillard-Baron, A. MebazaaP020 - Impact of disease severity assessment on performance of heparin-binding protein for the prediction of septic shockR. Arnold, M. Capan, A. Linder, P. AkessonP021 - Kinetics and prognostic value of presepsin (sCD14) in septic patients. A pilot studyM. Popescu, D. TomescuP022 - Comparison of CD64 levels performed by the facs and accellix systemsC. L. Sprung, R. Calderon Morales, G. Munteanu, E. Orenbuch-Harroch, P. Levin, H. Kasdan, A. Reiter, T. Volker, Y. Himmel, Y. Cohen, J. MeissonnierP023 - Diagnosing sepsis in 5 minutes: Nanofluidic technology study with pancreatic-stone protein (PSP/ reg)L. Girard, F. RebeaudP024 - How nanotechnology-based approaches could contribute to sepsis prevention, diagnosis and treatmentI. HerrmannP025 - Il7r transcriptional expression analysis during septic shockB. Delwarde, E. Peronnet, E. Cerrato, F. Venet, A. Lepape, T. Rimmelé, G. Monneret, J. TextorisP026 - Disbalance of microbial metabolites of aromatic acids affects the severity in critically ill patientsN. Beloborodova, V. Moroz, A. Osipov, A. Bedova, Y. Sarshor, A. Pautova, A. Sergeev, E. ChernevskayaP027 - Copeptin predicts 10-year all-cause mortality in community patientsJ. Odermatt, R. Bolliger, L. Hersberger, M. Ottiger, M. Christ-Crain, B. Mueller, P. SchuetzP028 - Identification of differential proteomic response in septic patients secondary to community and hospital acquired pneumoniaN. K. Sharma, A. K. Tashima, M. K. Brunialti, F. R. Machado, M. Assuncao, O. Rigato, R. SalomaoP029 - Monocyte HLA-DR expression in community-acquired bacteremic sepsis - dynamics associated to aetiology and prediction of secondary sepsisS. C. Cajander, G. Rasmussen, E. Tina, B. Söderquist, J. Källman, K. StrålinP030 - Soluble B- and T-lymphocyte attenuator: A possible prognostic marker in sepsisA. L. Lange, J. S. Sundén-Cullberg, A. M. Magnuson, O. H. HultgrenP031 - Fractal dimension: A new biomarker for quantifying clot microstructure in patients across the sepsis spectrumG. Davies, S. Pillai, G. Mills, R. Aubrey, K. Morris, P. Williams, P. EvansP032 - Comparison between the new biomarker for coagulation, clot microstructure (Df) with rotational thromboelastometry (ROTEM) in patients across the sepsis spectrumS. Pillai, G. Davies, G. Mills, R. Aubrey, K. Morris, P. Williams, P. EvansP033 - Changes in fibrinolysis across the sepsis spectrum: The use of rotational thromboelastometry (ROTEM) lysis index (LI60) and D-Dimer concentrationS. Pillai, G. Davies, G. Mills, R. Aubrey, K. Morris, P. Williams, P. EvansP034 - The intensive care infection score – a promising marker for the prediction of infection and its severity.P. Van der Geest, M. Mohseni, J. Linssen, R. De Jonge, S. Duran, J. GroeneveldP035 - Challenges in the clinical diagnosis of sepsisR. Miller III, B. K. Lopansri, L. C. McHugh, A. Seldon, J. P. BurkeP036 - Does zero heat flux thermometry more accurately identify sepsis on intensive care?J. Johnston, R. Reece-Anthony, A. Bond, A. MolokhiaP037 - Advancing quality (AQ) sepsis programme: Improving early identification & treatment of sepsis in North West England.C. Mcgrath, E. NsutebuP038 - Prehospital transport of acute septic patientsP. Bank Pedersen, D. Pilsgaard Henriksen, S. Mikkelsen, A. Touborg LassenP039 - Vasodilatory plant extracts gel as an alternative treatment for fever in critically ill patientsR. Tincu, C. Cobilinschi, D. Tomescu, Z. Ghiorghiu, R. MacoveiP040 - Host response and outcome of hypothermic sepsisM. A. Wiewel, M. B. Harmon, L. A. Van Vught, B. P. Scicluna, A. J. Hoogendijk, J. Horn, A. H. Zwinderman, O. L. Cremer, M. J. Bonten, M. J. Schultz, T. Van der Poll, N. P. Juffermans, W. J. WiersingaP041 - Septic shock alert over SIRS criteria has an impact on outcome but needs to be revisedG. Eren, Y Tekdos, M. Dogan, O. Acicbe, E. Kaya, O. HergunselP042 - Association between previous prescription of βblockers and mortality rate among septic patients: A retrospective observational studyS. Alsolamy, G. Ghamdi, L. Alswaidan, S. Alharbi, F. Alenezi, Y. ArabiP043 - Recognition and treatment of sepsis on labour ward– teaching & information resources can improve knowledgeJ. Heaton, A. Boyce, L. Nolan, J. Johnston, A. Dukoff-Gordon, A. Dean, A. MolokhiaP044 - Culture negative sepsis in the ICU – what is unique to this patient population?T. Mann Ben YehudahP045 - Organ dysfunction in severe sepsis patients identified in administrative data in Germany, 2007-2013C. Fleischmann, D. Thomas-Rueddel, C. Haas, U. Dennler, K. ReinhartP046 - A comparison of residents’ knowledge regarding; the Surviving Sepsis Campaign 2012 guidelineO. Suntornlohanakul, B. KhwannimitP047 - Effectiveness of a septic shock bundle to improve outcomes in the ICUF. Breckenridge, A. PuxtyP048 - Dose of norepinephrine in the first 24 hours as a parameter evaluating the effectiveness of treatment in patients with severe sepsis and septic shockP. Szturz, P. Folwarzcny, J. Svancara, R. Kula, P. SevcikP049 - Norepinephrine or vasopressin + norepinephrine in septic shock. A retrospective series of 39 patientsL. Caneva, A. Casazza, E. Bellazzi, S. Marra, L. Pagani, M. Vetere, R. Vanzino, D. Ciprandi, R. Preda, R. Boschi, L. CarnevaleP050 - Methylene blue effectiveness as contributory treatment in patients with septic shockV. Lopez, M. Aguilar Arzapalo, L. Barradas, A. Escalante, J. Gongora, M. CetinaP051 - Coagulation disorders in patients with severe sepsis and DIC evaluated with thromboelastometry.B Adamik, D Jakubczyk, A KüblerP052 - Frequency and outcome of early sepsis-associated coagulopathyA. Radford, T. Lee, J. Singer, J. Boyd, D. Fineberg, M. Williams, J. RussellP053 - Assessment of coagulopathy in cancer patients with severe sepsis or septic shock. A case-control pilot studyE. Scarlatescu, D. Tomescu, G. Droc, S. AramaP054 - Thromboelastometry in critically ill patients with disseminated intravascular coagulationM. Müller, M. Straat, S. S. Zeerleder, N. P. JuffermansP055 - Cessation of a preexisting chronic antiplatelet therapy is associated with increased mortality rates in severe sepsis and septic shockC. F. Fuchs, C. S. Scheer, S. W. Wauschkuhn, M. V. Vollmer, K. M. Meissner, S. K. Kuhn, K. H. Hahnenkamp, S. R. Rehberg, M. G. GründlingP056 - Neutrophil Extracellular Traps (NETs) production under hypoxic conditionN. Yamamoto, M. Ojima, S. Hamaguchi, T. Hirose, Y. Akeda, R. Takegawa, O. Tasaki, T. Shimazu, K. TomonoP057 - Impact of ultraviolet air sterilizer in intensive care unit room, and clinical outcomes of patientsE. Gómez-Sánchez, M. Heredia-Rodríguez, E. Álvarez-Fuente, M. Lorenzo-López, E. Gómez-Pesquera, M. Aragón-Camino, P. Liu-Zhu, A. Sánchez-López, A. Hernández-Lozano, M. T. Peláez-Jareño, E. TamayoP058 - Focus of infection in severe sepsis - comparison of administrative data and prospective cohorts from GermanyD. O. Thomas-Rüddel, C. Fleischmann, C. Haas, U. Dennler, K. ReinhartP059 - “Zero CLABSI” – can we get there? Obstacles on the 4 year journey and our strategies to overcome them – experience from an Indian ICUV. Adora, A. Kar, A. Chakraborty, S. Roy, A. Bandyopadhyay, M. DasP060 - Novel molecular techniques to identify central venous catheter (CVC) associated blood stream infections (BSIs)T. Mann Ben Yehudah, G. Ben Yehudah, M. Salim, N. Kumar, L. Arabi, T. Burger, P. Lephart, E. Toth-martinP061 - Zero clabsi” – can we get there? Obstacles on the 4 year journey and our strategies to overcome them – experience from an Indian ICUR. Rao, A. Kar, A. ChakrabortyP062 - Prevention of central line-associated bloodstream infections in intensive care units: An international online surveyC. Valencia, N. Hammami, S. Blot, J. L. Vincent, M. L. LambertP063 - 30 days antimicrobial efficacy of non-leaching central venous cathetersJ. Brunke, T. Riemann, I. RoschkeP064 - Efficacy of noble metal alloy-coated catheter in prevention of bacteriuriaR. Tincu, C. Cobilinschi, D. Tomescu, Z. Ghiorghiu, R. MacoveiP065 - Predicting bacteremic urinary tract infection in community setting: A prospective observational studyS. Nimitvilai, K. Jintanapramote, S. JarupongprapaP066 - Eight-year analysis of acinetobacter spp. monobacteremia in surgical and medical intensive care units at university hospital in LithuaniaD. Adukauskiene, D. ValancieneP067 - Group A and group B streptococcal infections in intensive care unit – our experience in a tertiary centreG. Bose, V. Lostarakos, B. CarrP068 - Improved detection of spontaneous bacterial peritonitis by uritop + tm strip test and inoculation of blood culture bottles with ascitic fluidS. Khedher, A. Maaoui, A. Ezzamouri, M. SalemP069 - Increased risk of cellulitis in patients with congestive heart failure: a population based cohort studyJ. ChenP070 - Outcomes of severe cellulitis and necrotizing fasciitis in the critically illD. R. Cranendonk, L. A. Van Vught, M. A. Wiewel, O. L. Cremer, J. Horn, M. J. Bonten, M. J. Schultz, T. Van der Poll, W. J. WiersingaP071 - Botulism outbreak associated with people who inject drugs (PWIDs) in Scotland.M. Day, G. Penrice, K. Roy, P. Robertson, G. Godbole, B. Jones, M. Booth, L. DonaldsonP072 - Surveillance of ESBL-producing enterobacteriaceae fecal carriers in the ICUY. Kawano, H. IshikuraP073 - Prevalence of ESBL and carbapenemase producing uropathogens in a newly opened hospital in south IndiaS. Sreevidya, N. Brahmananda Reddy, P. Muraray Govind, R. Pratheema, J. DevachandranApollo Speciality Hospital - OMR, Chennai, IndiaP074 - Prevalence, risk factors and outcomes of methicillin-resistant staphylococcus aureus nasal colonization in critically ill patientsH. Al-Dorzi, M. Almutairi, B. Alhamadi, A. Crizaldo Toledo, R. Khan, B. Al Raiy, Y. ArabiP075 - Multidrug-resistant Acinetobacter baumannii infection in intensive care unit patients in a hospital with building construction: Is there an association?H. TalaieP076 - Multidrug-resistant organisms in a Dutch ICUJ. A. Van Oers, A. Harts, E. Nieuwkoop, P. VosP077 - Epidemiology and risk factors of ICU acquired infections caused by multidrug-resistant gram negative bacilliY. Boussarsar, F. Boutouta, S. Kamoun, I. Mezghani, S. Koubaji, A. Ben Souissi, A. Riahi, M. S. MebazaaP078 - Improving outcomes of severe infections by multidrug-resistant pathogens with polyclonal IgM-enriched immunoglobulinsE. Giamarellos-Bourboulis, N. Tziolos, C. Routsi, C. Katsenos, I. Tsangaris, I. Pneumatikos, G. Vlachogiannis, V. Theodorou, A. Prekates, E. Antypa, V. Koulouras, N. Kapravelos, C. Gogos, E. Antoniadou, K. Mandragos, A. ArmaganidisP079 - Must change the medical practice in ICU?A. R. Robles Caballero, B. Civantos, J. C. Figueira, J. LópezP080 - Mediterranean spotted fever in an infectious diseases intensive care unitA. Silva-Pinto, F. Ceia, A. Sarmento, L. SantosP081 - Clinical features and outcomes of patients with Middle East respiratory syndrome requiring admission to a saudi intensive care unit: A retrospective analysis of 31 casesG. Almekhlafi, Y. SakrP082 - The ICU response to a hospital outbreak of Middle East respiratory syndrome coronavirus infectionH. Al-Dorzi, R. Khan, S. Baharoon, A. Aldawood, A. Matroud, J. Alchin, S. Al Johani, H. Balkhy, Y. ArabiP083 - Middle East respiratory syndrome: Surveillance data analysisS. Alsolamy, S. Y. Yousif, B. O. Alotabi, A. S. AlsaawiP085 - Use of Taqman array card molecular diagnostics in severe pneumonia: A case seriesJ. Ang, MD Curran, D. Enoch, V. Navapurkar, A. Conway MorrisP086 - ‘BUNS’: An investigation protocol improves the ICU management of pneumoniaR. Sharvill, J. AstinP087 - Pneumonia in patients following secondary peritonitis: epidemiological features and impact on mortalityM. Heredia-Rodríguez, E. Gómez-Sánchez, M. T. Peláez-Jareño, E. Gómez-Pesquera, M. Lorenzo-López, P. Liu-Zhu, M. Aragón-Camino, A. Hernández-Lozano, A. Sánchez-López, E. Álvarez-Fuente, E. TamayoP088 - The use of the “CURB-65 score” by emergency room clinicians in a large teaching hospitalJ. Patel, C. KrugerP089 - Incidence of community acquired pneumonia with viral infection in mechanically ventilated patients in the medical intensive care unitJ. O’Neal, H. Rhodes, J. JancikP090 - The SAATELLITE Study: Prevention of S aureus Nosocomial Pneumonia (NP) with MEDI4893, a Human Monoclonal Antibody (mAb) Against S aureusB. François, P. F. Laterre, P. Eggimann, A. Torres, M. Sánchez, P. F. Dequin, G. L. Bassi, J. Chastre, H. S. JafriP091 - Risk factors and microbiological profile for nosocomial infections in trauma patientsM. Ben Romdhane, Z. Douira, S. Kamoun, M. Bousselmi, A. Ben Souissi, Y. Boussarsar, A. Riahi, M.S. MebazaaP092 - Correlation between percentages of ventilated patients developed vap and use of antimicrobial agents in ICU patients.A. Vakalos, V. AvramidisP093 - A comparison of two ventilator associated pneumonia surveillance techniquesT. H. Craven, G. Wojcik, K. Kefala, J. McCoubrey, J. Reilly, R. Paterson, D. Inverarity, I. Laurenson, T. S. WalshP094 - Lung ultrasound before and after fiberbronchoscopy - modifications may improve ventilator-associated pneumonia diagnosisS. Mongodi, B. Bouhemad, A. Orlando, A. Stella, G. Via, G. Iotti, A. Braschi, F. MojoliP095 - Comparing the accuracy of predictors of mortality in ventilator-associated pneumoniaM. Haliloglu, B. Bilgili, U. Kasapoglu, I. Sayan, M. Süzer Aslan, A. Yalcın, I. CinelP096 - Impact of pRBCs transfusion on percentage of ventilated patients developed VAP in ICU patientsA. Vakalos, V. AvramidisP097 - The impact of a series of interventions on the rate of ventilator associated pneumonia in a large teaching hospitalH. E. Ellis, K. Bauchmuller, D. Miller, A TempleP098 - The EVADE study: Prevention of Nosocomial Pneumonia (NP) caused by P aeruginosa with MEDI3902, a Novel Bispecific Monoclonal Antibody, against P aeruginosa virulence factorsJ. Chastre, B. François, A. Torres, C. E. Luyt, M. Sánchez, M. Singer, H. S. JafriP099 - Short-term inhaled colistin adjunctive therapy for ventilator-associated pneumoniaY. Nassar, M. S. AyadP100 - Effect of aerosolised colistin on weaning from mechanical ventilationA. Trifi, S. Abdellatif, F. Daly, R. Nasri, S. Ben LakhalP101 - Septic shock is an independent risk factor for colistin-induced severe acute kidney injury: a retrospective cohort studyB. Bilgili, M. Haliloglu, F. Gul, I. CinelP102 - Nosocomial pneumonia - emphasis on inhaled tobramycinA. Kuzovlev, A. Shabanov, S. Polovnikov, V. MorozP103 - In vitro evaluation of amikacin inhale and commercial nebulizers in a mechanical ventilatorN. Kadrichu, T. Dang, K. Corkery, P. ChallonerP104 - The effects of nebulized amikacin/fosfomycin and systemic meropenem on severe amikacin-resistant meropenem-susceptible P.aeruginosa pneumoniaG. Li Bassi, E. Aguilera, C. Chiurazzi, C. Travierso, A. Motos, L. Fernandez, R. Amaro, T. Senussi, F. Idone, J. Bobi, M. Rigol, A. TorresP105 - Optimization of gentamicin peak concentrations in critically ill patientsC. J. Hodiamont, N. P. Juffermans, J. M. Janssen, C. S. Bouman, R. A. Mathôt, M. D. De Jong, R. M. Van HestP106 - Systematic review of cefepime induced neurotoxicityL. Payne, G. L. FraserP107 - Unasyn® causes QT prolongation during treatment of intensive care patientsB. Tudor, M. Lahner, G. Roth, C. KrennP108 - Comparative study between teicoplanin and vancomycin in methicillin-resistant staphylococcus aureus (mrsa) infectious of toxicological intensive care unit (ticu) patients – Tehran, IranH. TalaieP109 - Phage therapy against antimicrobial resistance, design of the first clinical study phagoburnP. Jault, J. Gabard, T. Leclerc, S. Jennes, Y. Que, A. Rousseau, F. RavatP110 - Antibiotic dosing errors in critically ill patients with severe sepsis or septic shockH. Al-Dorzi, A. Eissa, S. Al-Harbi, T. Aldabbagh, R. Khan, Y. ArabiP111 - Does empiric antifungal therapy improve survival in septic critically ill patients? (immunocompromised excluded)A. Trifi, S. Abdellatif, F. Daly, R. Nasri, S. Ben LakhalP112 - Neurocysticercosis-Qatar experienceF. Paramba, N. Purayil, V. Naushad, O. Mohammad, V. Negi, P. ChandraP113 - Early indicators in acute haemorrhagic shockA. KleinsasserP114 - Filtering of red blood cells reduces the inflammatory response of pulmonary cells in an in vitro model of mechanical ventilationM. R. Witrz, J. F. Buchner-Doeven, A. M. Tuip-de Boer, J. C. Goslings, N. P. JuffermansP115 - Microparticles from red blood cell transfusion induce a pro-coagulant and pro-inflammatory endothelial cell responseM. Van Hezel, M. Straat, A Boing, R Van Bruggen, N JuffermansP116 - The contribution of cytokines on thrombosis development during hospitalization in ICUD. Markopoulou, K. Venetsanou, V. Kaldis, D. Koutete, D. Chroni, I. AlamanosP117 - Prophylactic enoxaparin dosing and adjustment through anti-xa monitoring in an inpatient burn unitL. Koch, J. Jancik, H. Rhodes, E. WalterP118 - Determination of optimal cut-off values of haemoglobin, platelet count and fibrinogen at 24 hours after injury associated with mortality in trauma patientsK. Maekawa, M. Hayakawa, S. Kushimoto, A. Shiraishi, H. Kato, J. Sasaki, H. Ogura, T. Matauoka, T. Uejima, N. Morimura, H. Ishikura, A. Hagiwara, M. TakedaP119 - Trauma-induced coagulopathy - prothrombin complex concentrate vs fresh frozen plasmaO. Tarabrin, S. Shcherbakow, D. Gavrychenko, G. Mazurenko, V. Ivanova, O. ChystikovP120 - First study to prove the superiority of prothrombin complex concentrates on mortality rate over fresh frozen plasma in patients with acute bleedingC. Plourde, J. Lessard, J. Chauny, R. DaoustP121 - Prothrombin complex concentrate vs fresh frozen plasma in obstetric massive bleedingS. Shcherbakow, O. Tarabrin, D. Gavrychenko, G. Mazurenko, O. ChystikovP122 - Impact of FFP transfusion on VAP in ICU patientsA. Vakalos, V. AvramidisP123 - Preoperative platelet function test and the thrombin generation assay are predictive for blood loss after cardiac surgeryL. Kropman, L. In het Panhuis, J. Konings, D. Huskens, E. Schurgers, M. Roest, B. De Laat, M. LanceP124 - Rotational thromboelastometry versus standard coagulation tests before surgical interventionsM. Durila, P. Lukas, M. Astraverkhava, J. JonasP125 - Correction of impaired clot quality and stability by fibrinogen and activated prothrombin complex concentrate in a model of severe thrombocytopeniaI. Budnik, B. ShenkmanP126 - Assessment of point-of-care prothrombin time analyzer as a monitor after cardiopulmonary bypassH. Hayami, Y. Koide, T. GotoP127 - Disseminated intravascular coagulation (dic) is underdiagnosed in critically ill patients: do we need d-dimer measurements?R. Iqbal, Y. Alhamdi, N. Venugopal, S. Abrams, C. Downey, C. H. Toh, I. D. WeltersP128 - Validity of the age-adjusted d-dimer cutoff in patients with COPDB. Bombay, J. M. Chauny, R. D. Daoust, J. L. Lessard, M. M. Marquis, J. P. PaquetP129 - A scoping review of strategies for prevention and management of bleeding following paediatric cardiopulmonary bypass surgeryK. Siemens, D. Sangaran, B. J. Hunt, A. Durward, A. Nyman, I. A. Murdoch, S. M. TibbyP130 - Nadir hemoglobulin during cardiopulmonary bypass: impact on postoperative morbidity and mortalityF. Ampatzidou, D. Moisidou, E. Dalampini, M. Nastou, E. Vasilarou, V. Kalaizi, H. Chatzikostenoglou, G. DrossosP131 - Red blood cell transfusion do not influence the prognostic value of RDW in critically ill patientsS. Spadaro, A. Fogagnolo, T. Fiore, A. Schiavi, V. Fontana, F. Taccone, C. VoltaP132 - Reasons for admission in the paediatric intensive care unit and the need for blood and blood products transfusionsE. Chochliourou, E. Volakli, A. Violaki, E. Samkinidou, G. Evlavis, V. Panagiotidou, M. SdougkaP133 - The implementation of a massive haemorrhage protocol (mhp) for the management of major trauma: a ten year, single-centre studyR. Mothukuri, C. Battle, K. Guy, G. Mills, P. EvansP134 - An integrated major haemorrhage protocol for pre-hospital and retrieval medical teamsJ. Wijesuriya, S. KeoghP135 - The impact of transfusion thresholds on mortality and cardiovascular events in patients with cardiovascular disease (non-cardiac surgery): a systematic review and meta-analysisA. Docherty, R. O’Donnell, S. Brunskill, M. Trivella, C. Doree, L. Holst, M. Parker, M. Gregersen, J. Almeida, T. Walsh, S. StanworthP136 - The relationship between poor pre-operative immune status and outcome from cardiac surgery is specific to the peri-operative antigenic threatS. Moravcova, J. Mansell, A. Rogers, R. A. Smith, C. Hamilton-DaviesP137 - Impact of simple clinical practice guidelines for reducing post-operative atrial fibrillation after cardiac surgery.A. Omar, M. Allam, O. Bilala, A. Kindawi, H. EwilaP138 - Dexamethasone administration during cardiopulmonary bypass has no beneficial effects on elective postoperative cardiac surgery patientsF. Ampatzidou, D. Moisidou, M. Nastou, E. Dalampini, A. Malamas, E. Vasilarou, G. DrossosP139 - Intra-aortic balloon counterpulsation in patients undergoing cardiac surgery (IABCS): preliminary resultsG. Ferreira, J. Caldas, J. Fukushima, E. A. Osawa, E. Arita, L. Camara, S. Zeferino, J. Jardim, F. Gaioto, L. Dallan, F. B. Jatene, R. Kalil Filho, .F Galas, L. A. HajjarP140 - Effects of low-dose atrial natriuretic peptide infusion on cardiac surgery-associated acute kidney injuryC. Mitaka, T. Ohnuma, T. Murayama, F. Kunimoto, M. Nagashima, T. Takei, M. TomitaP141 - Acute kidney injury influence on high sensitive troponin measurements after cardiac surgeryA. Omar, K. Mahmoud, S. Hanoura, S. Sudarsanan, P. Sivadasan, H. Othamn, Y. Shouman, R. Singh, A. Al KhulaifiP142 - Complex evaluation of endothelial dysfunction markers for prognosis of outcomes in patients undergoing cardiac surgeryI. Mandel, S. Mikheev, I. Suhodolo, V. Kiselev, Y. Svirko, Y. PodoksenovP143 - New-onset atrial fibrillation in intensive care: incidence, management and outcomeS. A. Jenkins, R. GriffinP144 - One single spot measurement of the sublingual microcirculation during acute pulmonary hypertension in a pig model of shockM. S. Tovar Doncel, A. Lima, C. Aldecoa, C. InceP145 - Assessment of levosimendan as a therapeutic option to recruit the microcirculation in cardiogenic shock – initial experience in cardiac ICUA. Taha, A. Shafie, M. Mostafa, N. Syed, H. HonP146 - Terlipressin vs. norepinephrine in the Potential Multiorgan Donor(PMD)F. Righetti, E. Colombaroli, G. CastellanoP147 - Echocardiography in the potential heart donor exposed to substitution hormonotherapyF. Righetti, E. ColombaroliP148 - Machine learning can reduce rate of monitor alarmsM. Hravnak, L. C. Chen, A. D. Dubrawski, G. C. Clermont, M. R. PinskyP149 - Peripherally inserted central catheters placed in the ICUS. Gonzalez, D. Macias, J. Acosta, P. Jimenez, A. Loza, A. Lesmes, F. Lucena, C. LeonP150 - Recordings of abnormal central venous pressure waveform morphology during an episode of pulmonary hypertension in a porcine shock modelM. S. Tovar Doncel, C. Ince, C. Aldecoa, A. LimaP151 - Ultrasound guided central venous access technique among French intensivistsM. Bastide, J. Richecoeur, E. Frenoy, C. Lemaire, B. Sauneuf, F. Tamion, S. Nseir, D. Du Cheyron, H. Dupont, J. MaizelP152 - Predictive ability of the Pv-aCO2 gap in patients with shockM. Shaban, R. Kolko, N. Salahuddin, M. Sharshir, M. AbuRageila, A. AlHussainP153 - Comparison of echocardiography and pulmonary artery catheter measurements of hemodynamic parameters in critical ill patientsP. Mercado, J. Maizel, L. Kontar, D. Titeca, F. Brazier, A. Riviere, M. Joris, T. Soupison, B. De Cagny, M. SlamaP154 - The volume clamp method for noninvasive cardiac output measurement in postoperative cardiothoracic surgery patients: a comparison with intermittent pulmonary artery thermodilutionJ. Wagner, A. Körner, M. Kubik, S. Kluge, D. Reuter, B. SaugelP155 - Hemodynamic monitoring in patients with septic shock (SS) – CPCCO (continuous pulse contour cardiac output) vs. TEE (transesophageal echocardiography)E. Colombaroli, F. Righetti, G. CastellanoP156 - Cardiac output measurement with transthoracic echocardiography in critically ill patients: a pragmatic clinical studyT. Tran, D. De Bels, A. Cudia, M. Strachinaru, P. Ghottignies, J. Devriendt, C. PierrakosP157 - Left ventricular outflow tract velocity time integral correlates with stroke volume index in mechanically ventilated patientsÓ. Martínez González, R. Blancas, J. Luján, D. Ballesteros, C. Martínez Díaz, A. Núñez, C. Martín Parra, B. López Matamala, M. Alonso Fernández, M. ChanaP158 - Transpulmonary thermodilution (TPTD) derived from femoral vs. jugular central venous catheter: validation of a previously published correction formula and a proprietary correction formula for global end-diastolic volume index (GEDVI)W. Huber, M. Eckmann, F. Elkmann, A. Gruber, I. Klein, R. M. Schmid, T. LahmerP160 - Dynamic arterial elastance calculated with lidcoplus monitor does not predict changes in arterial pressure after a fluid challenge in postsurgical patientsD. Bastoni, H. Aya, L. Toscani, L. Pigozzi, A. Rhodes, M. CecconiP159 - Venous return driving pressure and resistance in acute blood volume changesP. W. Moller, S. Sondergaard, S. M. Jakob, J. Takala, D. BergerP160 - Dynamic arterial elastance calculated with lidcoplus monitor does not predict changes in arterial pressure after a fluid challenge in postsurgical patientsD. Bastoni, H. Aya, L. Toscani, L. Pigozzi, A. Rhodes, M. CecconiP161 - Analysis of duration of post-operative goal-directed therapy protocolC. Ostrowska, H. Aya, A. Abbas, J. Mellinghoff, C. Ryan, D. Dawson, A. Rhodes, M. CecconiP162 - Hemodynamic optimization – back to square one?M. Cronhjort, O. Wall, E. Nyberg, R. Zeng, C. Svensen, J. Mårtensson, E. Joelsson-AlmP163 - Effectiveness of fluid thoracic content measurement by bioimpedance guiding intravascular volume optimization in patients with septic shockM. Aguilar Arzapalo, L. Barradas, V. Lopez, M. CetinaP164 - A systematic review on the role of internal jugular vein ultrasound measurements in assessment of volume status in critical shock patientsN. Parenti, C. Palazzi, L. A. Amidei, F. B. Borrelli, S. C. Campanale, F. T. Tagliazucchi, G. S. Sedoni, D. L. Lucchesi, E. C. Carella, A. L LucianiP165 - Importance of recognizing dehydration in medical Intensive Care UnitM. Mackovic, N. Maric, M. BakulaP166 - Effect of volume for a fluid challenge in septic patientsH. Aya, A. Rhodes, R. M. Grounds, N. Fletcher, M. CecconiP167 - Fluid bolus practices in a large Australian intensive care unitB. Avard, P. ZhangP168 - Liberal late fluid management is associated with longer ventilation duration and worst outcome in severe trauma patients: a retrospective cohort of 294 patientsM. Mezidi, J. Charbit, M. Ould-Chikh, P. Deras, C. Maury, O. Martinez, X. CapdevilaP169 - Association of fluids and outcomes in emergency department patients hospitalized with community-acquired pneumoniaP. Hou, W. Z. Linde-Zwirble, I. D. Douglas, N. S. ShapiroP170 - Association of positive fluid balance with poor outcome in medicosurgical ICU patientsA. Ben Souissi, I. Mezghani, Y. Ben Aicha, S. Kamoun, B. Laribi, B. Jeribi, A. Riahi, M. S. MebazaaP171 - Impact of fluid balance to organ dysfunction in critically ill patientsC. Pereira, R. Marinho, R. Antunes, A. MarinhoP172 - Volume bolus in ICU patients: do we need to balance our crystalloids?M. Crivits, M. Raes, J. Decruyenaere, E. HosteP173 - The use of 6 % HES solution do not reduce total fluid requirement in the therapy of patients with burn shockV. Bagin, V. Rudnov, A. Savitsky, M. Astafyeva, I. Korobko, V. VeinP174 - Electron microscopic assessment of acute kidney injury in septic sheep resuscitated with crystalloids or different colloidsT. Kampmeier , P. Arnemann, M. Hessler, A. Wald, K. Bockbreder, A. Morelli, H. Van Aken, S. Rehberg, C. ErtmerP175 - Alterations of conjunctival microcirculation in a sheep model of haemorrhagic shock and resuscitation with 0.9 % saline or balanced tetrastarchP. Arnemann, M. Hessler, T. Kampmeier, S. Rehberg, H. Van Aken, C. Ince, C. ErtmerP176 - A single centre nested pilot study investigating the effect of using 0.9 % saline or Plasma-Lyte 148 ® as crystalloid fluid therapy on gastrointestinal feeding intolerance in mechanically ventilated patients receiving nasogastric enteral nutritionS. Reddy, M. Bailey, R. Beasley, R. Bellomo, D. Mackle, A. Psirides, P. YoungP177 - A single centre nested pilot study investigating the effect on post-operative bleeding of using 0.9 % saline or Plasma-Lyte® 148 as crystalloid fluid therapy in adults in ICU after heart surgeryS. Reddy, M. Bailey, R. Beasley, R. Bellomo, D. Mackle, P. YoungP178 - Extreme hypernatremia and sepsis in a patient with Huntington’s dementia: a conundrum in fluid managementH. Venkatesh, S. Ramachandran, A. Basu, H. NairP179 - Diagnosis and management of severe hypernatraemia in the critical care settingS. Egan, J. BatesP180 - Correlation between arterial blood gas and electrolyte disturbances during hospitalization and outcome in critically ill patientsS. Oliveira, N. R. Rangel Neto, F. Q. ReisP181 - Missing the “I” in MUDPILES – a rare cause of high anion gap metabolic acidosis (HAGMA)C. P. Lee, X. L. Lin, C. Choong , K. M. Eu, W. Y. Sim , K. S. Tee, J. Pau , J. AbisheganadenP182 - Plasma NGAL and urinary output: potential parameters for early initiation of renal replacement therapyK. Maas, H. De GeusP183 - Renal replacement therapy for critically ill patients: an intermittent continuityE. Lafuente, R. Marinho, J. Moura, R. Antunes, A. MarinhoP184 - A survey of practices related to renal replacement therapy in critically ill patients in the north of England.T. E. Doris, D. Monkhouse, T. Shipley, S. Kardasz, I GonzalezP185 - High initiation creatinine associated with lower 28-day mortality in critically ill patients necessitating continuous renal replacement therapyS. Stads, A. J. GroeneveldP186 - The impact of Karnofsky performance scale on outcomes in acute kidney injury patients receiving renal replacement therapy on the intensive care unitI. Elsayed, N. Ward, A. Tridente, A. RaithathaP187 - Severe hypophosphatemia during citrate-anticoagulated CRRTA. Steuber, C. Pelletier, S. Schroeder, E. Michael, T. Slowinski, D. Kindgen-MillesP188 - Citrate regional anticoagulation for post dilution continuous renal replacement therapyS. GhabinaP189 - Citrate 18 mmol/l improves anticoagulation during RRT with adsorbing filtersF. Turani, A. Belli, S. Busatti, G. Barettin, F. Candidi, F. Gargano, R. Barchetta, M. FalcoP190 - Calcium gluconate instead of calcium chloride in citrate-anticoagulated CVVHDO. Demirkiran, M. Kosuk, S. BozbayP191 - Enhanced clearance of interleukin-6 with continuous veno-venous haemodialysis (CVVHD) using Ultraflux EMiC2 vs. Ultraflux AV1000SV. Weber, J. Hartmann, S. Harm, I. Linsberger, T. Eichhorn, G. Valicek, G. Miestinger, C. HoermannP192 - Removal of bilirubin with a new adsorbent system: in vitro kineticsS. Faenza, D. Ricci, E. Mancini, C. Gemelli, A. Cuoghi, S. Magnani, M. AttiP193 - Case series of patients with severe sepsis and septic shock treated with a new extracorporeal sorbentT. Laddomada, A. Doronzio, B. BaliccoP194 - In vitro adsorption of a broad spectrum of inflammatory mediators with CytoSorb® hemoadsorbent polymer beadsM. C. Gruda, P. O’Sullivan, V. P. Dan, T. Guliashvili, A. Scheirer, T. D. Golobish, V. J. Capponi, P. P. ChanP195 - Observations in early vs. late use of cytosorb therapy in critically ill patientsK. Kogelmann, M. Drüner, D. JarczakP196 - Oxiris membrane decreases endotoxin during rrt in septic patients with basal EAA > 0,6F. Turani, A. B. Belli, S. M. Martni, V. C. Cotticelli, F. Mounajergi, R. BarchettaP197 - An observational prospective study on the onset of augmented renal clearance: the first reportS. Morimoto, H. IshikuraP198 - An ultrasound- guided algorithm for the management of oliguria in severe sepsisI. Hussain, N. Salahuddin, A. Nadeem, K. Ghorab, K. MaghrabiP199 - Ultrasound in acute kidney injury (aki). First findings of farius, an education-programme in structural ultrasonographyS. K. Kloesel, C. Goldfuss, A. Stieglitz, A. S. Stieglitz, L. Krstevska, G. AlbusziesP200 - Effectiveness of renal angina index score predicting acute kidney injury on critically ill patientsM. Aguilar Arzapalo, L. Barradas, V. Lopez, A. Escalante, G. Jimmy, M. CetinaP201 - Time length below blood pressure thresholds and progression of acute kidney injury in critically ill patients with or without sepsis: a retrospective, exploratory cohort studyJ. Izawa, T. Iwami, S. Uchino, M. Takinami, T. Kitamura, T. KawamuraP202 - Anaemia does not affect renal recovery in acute kidney injuryJ. G. Powell-Tuck, S. Crichton, M. Raimundo, L. Camporota, D. Wyncoll, M. OstermannP203 - Estimated glomerular filtration rate based on serum creatinine: actual practice in Dutch ICU’sA. Hana, H. R. De GeusP204 - Comparison of estimated glomerular filtration rate calculated by mdrd, ckd-epi-serum-creatinine and ckd-epi-cystatin-c in adult critically ill patientsH. R. De Geus, A. HanaP205 - Early diagnosis of septic acute kidney injury in medical critical care patients with a urine cell cycle arrest marker: insulin like growth factor binding protein-7 (IGFBP-7)M. Aydogdu, N. Boyaci, S. Yuksel, G. Gursel, A. B. Cayci SivriP206 - Urinary neutrophil gelatinase-associated lipocalin as early biomarker of severe acute kidney injury in intensive careJ. Meza-Márquez, J. Nava-López, R. Carrillo-EsperP207 - Shrunken pore syndrome is associated with a sharp rise in mortality in patients undergoing elective coronary artery bypass graftingA. Dardashti, A. GrubbP208 - The biomarker nephrocheck™ can discriminate the septic shock patients with an akin 1 or 2 acute renal failure who will not progress toward the akin 3 levelJ. Maizel, M. Wetzstein, D. Titeca, L. Kontar, F. Brazier, B. De Cagny, A. Riviere, T. Soupison, M. Joris, M. SlamaP209 - A worldwide multicentre evaluation of acute kidney injury in septic and non-septic critically ill patients: the intensive care over nations (icon) auditE. Peters, H. Njimi, P. Pickkers, J. L. VincentP210 - Does enhanced recovery after surgery reduce the incidence of acute kidney injury in those undergoing major gynae-oncological surgery?M. Waraich , J. Doyle, T. Samuels, L. ForniP211 - Identification of risk factors for the development of acute kidney injury after lower limb arthroplastyN. Desai, R. Baumber, P. Gunning, A. SellP212 - Incidences and associations of acute kidney injury after major traumaS. Lin, H. Torrence, M. O’Dwyer, C. Kirwan, J. ProwleP213 - Acute kidney injury of major trauma patientsT KimP214 - Trajectory of serum creatinine after major surgery and the diagnosis of acute kidney injuryM. E. O’Connor, R. W. Hewson, C. J. Kirwan, R. M. Pearse, J. ProwleP215 - Epidemiology of acute kidney injury after cardiac surgery. A single center retrospective studyS. Hanoura , A. Omar, H. Othamn, S. Sudarsanan , M. Allam, M. Maksoud, R. Singh, A. Al KhulaifiP216 - Post-operative acute kidney injury after major non-cardiac surgery and its association with death in the following yearM. E. O’Connor, R. W. Hewson, C. J. Kirwan, R. M. Pearse, J. ProwleP217 - Factors affecting acute renal failure in intensive care unit and effect of these factors on mortalityO. Uzundere, D. Memis , M. Ýnal, A. , N. TuranP218 - Results of the live kidney transplantations according to national data of turkish organ and tissue information systemM. A. Aydin, H. Basar, I. Sencan, A. Kapuagasi, M. Ozturk, Z. Uzundurukan, D. Gokmen, A. Ozcan, C. KaymakP219 - Anaesthesia procedure and intensive therapy in patients with neck phlegmonV. A. Artemenko, A. BudnyukP220 - Nasal high flow oygen for acute respiratory failure: a systematic reviewR. Pugh , S. BhandariP221 - Setting optimal flow rate during high flow nasal cannula support: preliminary resultsT. Mauri, C. Turrini, T. Langer, P. Taccone, C. A. Volta, C. Marenghi, L. Gattinoni, A. PesentiP222 - Dose to dose consistency across two different gas flow rates using cystic fibrosis and normal adult breathing profiles during nasal high flow oxygen therapyL. Sweeney, A . O’ Sullivan, P. Kelly, E. Mukeria, R. MacLoughlinP223 - Final results of an evaluation of airway medix closed suction system compared to a standard closed suction systemM. Pfeffer, J. T. Thomas, G. B. Bregman, G. K. Karp, E. K. Kishinevsky, D. S. Stavi, N. A. AdiP224 - Different cuff materials and different leak tests - one size does not fit allT. Poropat, R. KnafeljP225 - Observational study on the value of the cuff-leak test and the onset of upper airway obstruction after extubationE. Llopart, M. Batlle, C. De Haro, J. Mesquida, A. ArtigasP226 - A device for emergency transtracheal lung ventilationD. Pavlovic, L. Lewerentz, A. Spassov, R. SchneiderP227 - Long-term outcome and health-related quality of life in patients discharged from the intensive care unit with a tracheostomy and with or without prolonged mechanical ventilationS. De Smet, S. De Raedt, E. Derom, P Depuydt, S. Oeyen, D. Benoit, J. DecruyenaereP228 - Ultrasound-guided percutaneous dilational tracheostomy versus bronchoscopy-guided percutaneous dilational tracheostomy in critically ill patients (trachus): a randomized clinical trialA. Gobatto, B. Bese, P. Tierno, L. Melro, P. Mendes, F. Cadamuro, M. Park, L. M. MalbouissonP229 - Is it safe to discharge patients with tracheostomy from the ICU to the ward?B. C. Civanto, J. L. Lopez, A. Robles, J. Figueira, S. Yus, A. GarciaP230 - The application of tracheostomy in children in ICUA. Oglinda, G. Ciobanu, C. Oglinda, L. Schirca, T. Sertinean, V. LupuP231 - The impact of passive humidifiers on aerosol drug delivery during mechanical ventilationP. Kelly, A. O’Sullivan, L. Sweeney, R. MacLoughlinP232 - Evaluation of vibrating mesh and jet nebuliser performance at two different attachment setups in line with a humidifier nebuliser systemA. O’Sullivan, P. Kelly, L. Sweeney, E. Mukeria, M. Wolny , R. MacLoughlinP233 - Psv-niv versus cpap in the treatment of acute cardiogenic pulmonary edemaA. Pagano, F. Numis, G. Vison, L. Saldamarco, T. Russo, G. Porta, F. PaladinoP234 - Noninvasive ventilation in patients with haematologic malignancy: a retrospective reviewC. Bell, J. Liu, J. Debacker, C. Lee, E. Tamberg, V. Campbell, S. MehtaP235 - Use of non-invasive ventilation in infectious diseases besides classical indicationsA. Silva-Pinto, A. Sarmento, L. SantosP236 - The impact of fragility on noninvasive mechanical ventilation application and results in the ICUÝ. Kara, F. Yýldýrým, A. Zerman, Z. Güllü, N. Boyacý, B. Basarýk Aydogan, Ü. Gaygýsýz, K. Gönderen, G. Arýk, M. Turkoglu, M. Aydogdu, G. Aygencel, Z. Ülger, G. GurselP237 - Effects of metabolic alkalosis on noninvasive ventilation success and ICU outcome in patients with hypercapnic respiratory failureN. Boyacý, Z. Isýkdogan, Ö. Özdedeoglu, Z. Güllü, M. Badoglu, U. Gaygýsýz, M. Aydogdu, G. GurselP238 - Asynchrony index and breathing patterns of acute exacerbation copd patients assisted with noninvasive pressure support ventilation and neurally adjusted ventilatory assistN. Kongpolprom, C. SittipuntP239 - High frequency jet ventilation for severe acute hypoxemiaA. Eden, Y. Kokhanovsky, S. Bursztein – De Myttenaere, R. PizovP240 - HFOV revisited: a 7 year retrospective analysis of patients receiving HFOV who met oscillate trial entry criteriaL. Neilans, N. MacIntyreP241 - Implementation of a goal-directed mechanical ventilation order set driven by respiratory therapists can improve compliance with best practices for mechanical ventilationM. Radosevich, B. Wanta, V. Weber, T. Meyer, N. Smischney, D. Brown, D. DiedrichP242 - A reduction in tidal volumes for ventilated patients on ICU calculated from IBW. can it minimise mortality in comparison to traditional strategies?A . Fuller, P. McLindon, K. SimP243 - Predictive value of lung aeration scoring using lung ultrasound in weaning failureM. Shoaeir, K. Noeam, A. Mahrous, R. Matsa, A. AliP244 - Conventional versus automated weaning from mechanical ventilation using SmartCare™C. Dridi, S. Koubaji, S. Kamoun, F. Haddad, A. Ben Souissi, B. Laribi, A. Riahi, M. S. MebazaaP245 - Ultrasonographic evaluation protocol for weaning from mechanichal ventilationA. Pérez-Calatayud, R. Carrillo-Esper, A. Zepeda-Mendoza, M. Diaz-Carrillo, E. Arch-TiradoP246 - Diaphragm ultrasonography: a method for weaning patients from mechanical ventilationS. Carbognin, L. Pelacani, F. Zannoni, A. Agnoli, G. GagliardiP247 - Dorsal diaphragmatic excursion tracks transpulmonary pressure in ventilated ARDS patients: a potential non-invasive indicator of lung recruitment?R. Cho, A. Adams , S. Lunos, S. Ambur, R. Shapiro, M. PrekkerP248 - Pulse oximetry in the icu patient: is the perfusion index of any value?M. Thijssen, L. Janssen, N. FoudraineP249 - Ventilation is a better assessment of respiratory status than EtCO2C. J. Voscopoulos, J. FreemanP250 - Evaluation of the relationship between non-invasive minute ventilation and end-tidal CO2 in patients undergoing general vs spinal anesthesiaC. J. Voscopoulos, J. Freeman, E. GeorgeP251 - Respiratory volume monitoring provides early warning of respiratory depression and can be used to reduce false alarms in non-intubated patientsC. J. Voscopoulos, D. Eversole, J. Freeman, E. GeorgeP252 - P/i index: a predictive edi-derived weaning index during navaS. Muttini, R. Bigi, G. Villani, N. PatronitiP253 - Adequacy of ventilation in patients receiving opioids in the post anesthesia care unit: minute ventilation versus respiratory rateG. Williams, C. J. Voscopoulos, J. Freeman, E. GeorgeP254 - Comparison of regional and global expiratory time constants measured by electrical impedance tomography (EIT)A. Waldmann, S. Böhm, W. Windisch, S. Strassmann, C. KaragiannidisP255 - Electrical impedance tomography: robustness of a new pixel wise regional expiratory time constant calculationA. Waldmann, S. Böhm, W. Windisch, S. Strassmann, C. KaragiannidisP256 - Validation of regional and global expiratory time constant measurement by electrical impedance tomography in ards and obstructive pulmonary diseasesC. K. Karagiannidis, A. W. Waldmann, S. B. Böhm, S. Strassmann, W. W. WindischP257 - Transpulmonary pressure in a model with elastic recoiling lung and expanding chest wallP. Persson, S. Lundin, O. StenqvistP258 - Lactate in pleural and abdominal effusionG. Porta, F. Numis, C. S. Serra, A. P. Pagano, M. M. Masarone, L. R. Rinaldi, A. A. Amelia, M. F. Fascione, L. A. Adinolfi, E. R. RuggieroP259 - Outcome of patients admitted to the intensive care with pulmonary fibrosisF. Asota, K. O’Rourke, S. Ranjan, P. MorganP260 - Sedation and analgesia practice in extra-corporeal membrane oxygenation (ECMO)-treated patients with acute respiratory distress syndrome (ARDS): a retrospective studyJ. W. DeBacker, E. Tamberg, L. O’Neill, L. Munshi, L. Burry, E. Fan, S. MehtaP261 - Characteristics and outcomes of patients deemed not eligible when referred for veno-venous extracorporeal membrane oxygenation (vv-ECMO)S. Poo, K. Mahendran, J. Fowles, C. Gerrard, A. VuylstekeP262 - The SAVE SMR for veno-arterial ECMOR. Loveridge, C. Chaddock, S. Patel, V. Kakar, C. Willars, T. Hurst, C. Park, T. Best, A. Vercueil, G. AuzingerP263 - A simplified score to predict early (48 h) mortality in patients being considered for VA-ECMOA. Borgman, A. G. Proudfoot, E. Grins, K. E. Emiley, J. Schuitema, S. J. Fitch, G. Marco, J. Sturgill, M. G. Dickinson, M. Strueber, A. Khaghani, P. Wilton, S. M. JovingeP264 - Lung function six months post extra corporeal membrane oxygenation (ECMO) for severe acute respiratory failure in adult survivorsC. Sampson, S. Harris-FoxP265 - Bicarbonate dialysis removes carbon dioxide in hypoventilated rodents.M. E. Cove, L. H. Vu, A. Sen, W. J. Federspiel, J. A. KellumP266 - Procalcitonin as predictor of primary graft dysfunction and mortality in post-lung transplantationC. Mazo Torre, J. Riera, S. Ramirez, B. Borgatta, L. Lagunes, J. RelloP267 - New molecular biomarkers of acute respiratory distress syndrome in abdominal sepsisA. K. Kuzovlev, V. Moroz, A. Goloubev, S. Polovnikov, S. NenchukP268 - Tight junction’s proteins claudin -5 and regulation by tnf in experimental murine lung injury model of ali/ardsV. Karavana, C. Glynos, A. Asimakos, K. Pappas, C. Vrettou, M. Magkou, E. Ischaki, G. Stathopoulos, S. ZakynthinosP269 - Cell counts in endobronchial aspirate to assess airway inflammation in ARDS patients: a pilot studyS. Spadaro, I. Kozhevnikova, F. Dalla Corte, S. Grasso, P. Casolari, G. Caramori, C. VoltaP270 - Epidemiological and clinical profile of patients with acute respiratory distress syndrome in the surgical intensive care unit surgical, hospital JRA, AntananarivoT. Andrianjafiarinoa, T. Randriamandrato, T. RajaoneraP271 - Effect of high PEEP after recruitment maneuver on right ventricular function in ARDS. Is it good for the lung and for the heart?S. El-Dash, ELV Costa, MR Tucci, F Leleu, L Kontar, B. De Cagny, F. Brazier, D. Titeca, G. Bacari-Risal, J. Maizel, M. Amato, M. SlamaP272 - Effect of recruitment maneuver on left ventricular systolic strainP. Mercado, J. Maizel, L. Kontar, D. Titeca, F. Brazier, A. Riviere, M. Joris, T. Soupison, B. De Cagny, S. El Dash, M. SlamaP273 - Inhaled nitric oxide – is switching supplier cost effective?Remmington, A. Fischer, S. Squire, M. BoichatP274 - Epidemiological study of severe acute pancreatitis in Japan, comparison of the etiology and the patient outcomes on 1159 patients.H. Honzawa, H. Yasuda, T. Adati, S. Suzaki, M. Horibe, M. Sasaki, M. SanuiP275 - Extracorporeal liver support therapy. Experience in an intensive care unitR. Marinho, J. Daniel, H. Miranda, A. MarinhoP276 - Accuracy of mortality prediction models in acute versus acute-on-chronic liver failure in the intensive care settingK. Milinis, M. Cooper, G. R. Williams, E. McCarron, S. Simants, I. Patanwala, I. WeltersP277 - Risk of coronary artery disease in patients with chronic liver disease: a population based cohort studyY. SuP278 - 20 years of liver transplantation in Santiago de Compostela (Spain). Experience reviewJ. Fernández Villanueva, R. Fernández Garda, A. López Lago, E. Rodríguez Ruíz, R. Hernández Vaquero, S. Tomé Martínez de Rituerto, E. Varo PérezP279 - Diarrhea is a risk factor for liver injury and may lead to intestinal failure associated liver disease in critical illnessN. Lefel, F. Schaap, D. Bergmans, S. Olde Damink, M. Van de PollP280 - Bowel care on the intensive care unit: constipation guideline compliance and complicationsK. Tizard, C. Lister, L. PooleP281 - Malnutrition assessed by phase angle determines outcomes in low risk cardiac surgery patientsD. Ringaitiene, D. Gineityte, V. Vicka, I. Norkiene, J. SipylaiteP282 - Preoperative fasting times in an irish hospitalA. O’Loughlin, V. Maraj, J. DowlingP283 - Costs and final outcome of early x delayed feeding in a private Brazil ICUM. B. Velasco, D. M. Dalcomune, E. B. Dias, S. L. FernandesP284 - Can ventilator derived energy expenditure measurements replace indirect calorimetry?T. Oshima, S. Graf, C. Heidegger, L. Genton, V. Karsegard, Y. Dupertuis, C. PichardP285 - Revisiting the refeeding syndrome: results of a systematic reviewN. Friedli, Z. Stanga, B. Mueller, P. SchuetzP286 - Compliance with the new protocol for parenteral nutrition in our ICUL. Vandersteen, B. Stessel, S. Evers, A. Van Assche, L. Jamaer, J. DuboisP287 - Nutrition may be another treatment in the intensive care unit where less is more?R. Marinho, H. Castro, J. Moura, J. Valente, P. Martins, P. Casteloes, C. Magalhaes, S. Cabral, M. Santos, B. Oliveira, A. Salgueiro, A. MarinhoP288 - Should we provide more protein to critically ill patients?R. Marinho, M. Santos, E. Lafuente, H. Castro, S. Cabral, J. Moura, P. Martins, B. Oliveira, A. Salgueiro, S. Duarte, S. Castro, M. Melo, P. Casteloes, A. MarinhoP289 Protein provision in an adult intensive care unitS. GrayP290 - Prevalence and clinical outcomes of vitamin d deficiency in the medical critically ill patients in Songklanagarind hospitalK. Maipang, R. BhurayanontachaiP291 - Vitamin d deficiency strongly predicts adverse medical outcome across different medical inpatient populations: results from a prospective studyL. G. Grädel, P. SchützP292 - Omega-3 fatty acids in patients undergoing cardiac surgery: a systematic review and meta-analysisP. Langlois, W. ManzanaresP293 - Can 5-hydroxytriptophan prevent post-traumatic stress disorder in critically ill patients?R. Tincu, C. Cobilinschi, D. Tomescu, Z. Ghiorghiu, R. MacoveiP294 - Parenteral selenium in the critically ill: an updated systematic review and meta-analysisW. Manzanares, P. Langlois, M. Lemieux, G. Elke, F. Bloos, K. Reinhart, D. HeylandP295 - Probiotics in the critically ill: an updated systematic review and meta-analysisP. Langlois, M. Lemieux, I. Aramendi, D. Heyland, W. ManzanaresP296 - Diabetes with hyperglycemic crisis episodes may be associated with higher risk of pancreatic cancer: a population-based cohort studyY. SuP297 - Incidence of hypoglycemia in an intensive care unit depending on insulin protocolR. Marinho, N. Babo, A. MarinhoP298 - Severity of the diseases is two-dimensionally correlated to blood glucose, including blood glucose variability, especially in moderately to severely ill patients with glucose intolerance.M. Hoshino, Y. Haraguchi, S. Kajiwara, T. Mitsuhashi, T. Tsubata, M. AidaP299 - A study of glycemic control by subcutaneous glargine injection transition from continuous regular insulin infusion in critically ill patientsT. Rattanapraphat, R. Bhurayanontachai, C. Kongkamol, B. KhwannimitP300 - Glycemic control in Portuguese intensive care unitR. Marinho, M. Santos, H. Castro, E. Lafuente, A. Salgueiro, S. Cabral, P. Martins, J. Moura, B. Oliveira, M. Melo, B. Xavier, J. Valente, C. Magalhaes, P. Casteloes, A. MarinhoP301 - Impact of hyperglycemia duration on the day of operation on short-term outcome of cardiac surgery patientsD. Moisidou, F. Ampatzidou, C. Koutsogiannidis, M. Moschopoulou, G. DrossosP302 - Lactate levels in diabetic ketoacidosis patients at ICU admissionsG. Taskin, M. Çakir, AK Güler, A. Taskin, N. Öcal, S. Özer, L. YamanelP303 - Intensive care implications of merging heart attack centre units in LondonJ. M. Wong, C. Fitton, S. Anwar, S. StaceyP304 - Special characteristics of in-hospital cardiac arrestsM. Aggou, B. Fyntanidou, S. Patsatzakis, E. Oloktsidou, K. Lolakos, E. Papapostolou, V. GrosomanidisP305 - Clinical evaluation of ICU-admitted patients who were resuscitated in the general medicine wardS. Suda , T. Ikeda, S. Ono, T. Ueno, Y. IzutaniP306 - Serious game evaluation of a one-hour training basic life support session for secondary school students: new tools for future bystandersS. Gaudry, V. Desailly, P. Pasquier, PB Brun, AT Tesnieres, JD Ricard, D. Dreyfuss, A. MignonP307 - Public and clinical staff perceptions and knowledge of CPR compared to local and national dataJ. C White, A. Molokhia, A. Dean, A. Stilwell, G. FriedlaenderP308 Dispatcher-assisted telephone cardiopulmonary resuscitation using a French-language compression-ventilation pediatric protocolM. Peters, S. Stipulante, A. Delfosse, AF Donneau, A. GhuysenP309 Dantrolene versus amiodarone for resuscitation – an experimental studyC. Feldmann, D. Freitag, W. Dersch, M. Irqsusi, D. Eschbach, T. Steinfeldt, H. Wulf, T. WiesmannP310 Long term survival and functional neurological outcome in comatose survivors undergoing therapeutic hypothermiaN. Kongpolprom, J. CholkraisuwatP311 Impact of kidney disease on mortality and neurological outcome in out-of-hospital cardiac arrest: a prospective observational studyS. Beitland , E. Nakstad, H. Stær-Jensen , T. Drægni , G. Andersen , D. Jacobsen , C. Brunborg, B. Waldum-Grevbo , K. SundeP312 ICU dependency of patients admitted after primary percutaneous coronary intervention (PPCI) following out of the hospital cardiac arrestK. Hoyland, D. PanditP313 Prognostic indicators and outcome prediction model for patients with return of spontaneous circulation from cardiopulmonary arrest: comprehensive registry of in-hospital intensive care on OHCA survival (critical) study in Osaka, JapanK. HayakawaP314 Cerebral oxygen saturation during resuscitation in a porcine model of cardiac arrestE. Oloktsidou, K. Kotzampassi, B. Fyntanidou, S. Patsatzakis, L. Loukipoudi, E. Doumaki, V. GrosomanidisP315 Presumption of cardiopulmonary resuscitation for sustaining cerebral oxidation using regional cerebral saturation of oxygen: observational cohort study (press study)H. YasudaP316 EEG reactivity in patients after cardiac arrest: a close look at stimuliMM Admiraal, M. Van Assen, MJ Van Putten, M. Tjepkema-Cloostermans, AF Van Rootselaar, J. HornP317 Prognostic value of neuron-specific enolase after cardiac arrestF. Ragusa, A. Marudi , S. Baroni, A. Gaspari, E. BertelliniP318 Correlation between electroencephalographic findings and serum neuron specific enolase with outcome of post cardiac arrest patientsA. Taha, T. Abdullah, S. Abdel MonemP319 Introduction of a targeted temperature management strategy following cardiac arrest in a district general hospital intensive care unit.S. Alcorn, S. McNeill, S. RussellP320 The evolution of cerebral oxygen saturation in post-cardiac arrest patients treated with therapeutic hypothermiaW. Eertmans, C. Genbrugge, I. Meex, J. Dens, F. Jans, C. De DeyneP321 Prognostic factors and neurological outcomes of therapeutic hypothermia in comatose survivors from cardiac arrest: 8-year single center experienceJ. Cholkraisuwat, N. KongpolpromP322 Adherence to targeted temperature management after out of hospital cardiac arrestB. Avard, R. BurnsP323 Implementation of a therapeutic hypothermia protocol for comatose survivors of out-of-hospital cardiac arrest.A. Patarchi, T. SpinaP324 Factors associated with ventilator weaning after targeted temperature management for cardiac arrest patients in japanH. Tanaka, N. Otani, S. Ode, S. IshimatsuP325 Differential activation of c-fos in paraventricular nuclei of the hypothalamus and thalamus of the rat following myocardial infarctionJ. Cho, J. B. Moon, C. W. Park, T. G. Ohk, M. C. Shin, M. H. WonP326 Monitoring of cTroponin I in patients with acute ischemic stroke - predictor of inhospital mortalityS. Dakova, Z. Ramsheva, K. RamshevP327 Hyperthermic preconditioning severely accelerates neuronal damage in the gerbil ischemic hippocampal dentate gyrus via decreasing sods expressionsJ. Cho, J. B. Moon, C. W. Park, T. G. Ohk, M. C. ShinP328 Failure in neuroprotection of remote limb ischemic post conditioning in the hippocampus of a gerbil model of transient cerebral ischemiaJ. Cho, J. B. Moon, C. W. Park, T. G. Ohk, M. C. ShinP329 Brain death and admission diagnosis in neurologic intensive care unit, a correlation?A Marudi, S Baroni, A Gaspari, E BertelliniP330 Brain magnetic resonance imaging findings in patients with septic shockG. Orhun, E. Senturk, P. E. Ozcan, S. Sencer, C. Ulusoy, E. Tuzun, F . EsenP331 Benefits of L-carnitine in valproic acid induced encephalopathyR. Tincu, C. Cobilinschi, D. Tomescu, Z. Ghiorghiu, R. MacoveiP332Automatic analysis of EEG reactivity in comatose patientsM. Van Assen, M. M. Admiraal, M. J. Van Putten, M. Tjepkema-Cloostermans, A. F. Van Rootselaar, J. HornP333 Usefulness of common ICU severity scoring systems in predicting outcome after spontaneous intracerebral hemorrhageM. Fallenius, M. B. Skrifvars, M. Reinikainen, S. Bendel, R. RajP334 Evalution of patients with suspected subarachnoid haemorrhage and negative ct imagingM. Abu-Habsa, C. Hymers, A. Borowska, H. Sivadhas, S. Sahiba, S. PerkinsP335 Timing of endovascular and surgical treatment for aneurysmal subarachnoid haemorrhage: early but not so fast.J. Rubio, J. A. Rubio, R. SierraP336 Red blood cell transfusion in aneurysmal subarachnoid hemorrhage – the Sahara cohort studyS. English, M. Chasse, A. Turgeon, F. Lauzier, D. Griesdale, A. Garland, D. Fergusson, R. Zarychanski, A. Tinmouth, C. Van Walraven, K. Montroy, J. Ziegler, R. Dupont Chouinard, R. Carignan, A. Dhaliwal, C. Lum, J. Sinclair, G. Pagliarello, L. McIntyreP337 - Aneurysmal subarachnoid hemorrhage and anemia: a canadian multi-centre retrospective cohort studyS. English, M. Chasse, A. Turgeon, F. Lauzier, D. Griesdale, A. Garland, D. Fergusson, R. Zarychanski, A. Tinmouth, C. Van Walraven, K. Montroy, J. Ziegler, R. Dupont Chouinard, R. Carignan, A. Dhaliwal, C. Lum, J. Sinclair, G. Pagliarello, L. McIntyreP338 - Does the neutrophil-to-lymphocyte (NLR) ratio predict symptomatic vasospasm or delayed cerebral ischemia (DCI) after aneurysmal subarachnoid haemorrhage (SAH)?T. Groza, N. Moreau, D. Castanares-Zapatero, P. HantsonP339 - ICU-acquired infections in aneurysmal subarachnoid hemorrhage patients: impact on ICU and hospital length of stayM. Carbonara , F. Ortolano, T. Zoerle, S. Magnoni, S. Pifferi, V. Conte, N. StocchettiP340 - Cerebral metabolic effects of normobaric hyperoxia during the acute phase of aneurysmal subarachnoid hemorrhageL. Carteron, T. Suys, C. Patet, H. Quintard, M. OddoP341 - Postoperative care for elective craniotomy: where is best done?J. A. Rubio, J. Rubio, R. SierraP342 - 5-year follow-up of patients after transplantation of organs from donors from neurocritical careV. Spatenkova, E. Pokorna, P. SuchomelP343 - Evaluation of levetiracetam pharmacokinetics after severe traumatic brain injury in neurocritical care patients at a level one trauma centerN. Ebert, J. Jancik, H. RhodesP344 - Model based time series cluster analysis to determine unique patient states in traumatic brain injuryT. Bylinski, C. Hawthorne, M. Shaw, I. Piper, J. KinsellaP345 - Brain compartment monitoring capabilities from ICP to BI (bioimpedance) during HS (hypertonic saline) administration. State of art simulation outcome depending on brain swelling typeA. K. Kink , I. R. RätsepP346 - Transfusion of red blood cells in patients with traumatic brain injury admitted to Canadian trauma health centers: a multicenter cohort studyA. Boutin, L. Moore, M. Chasse, R. Zarychanski, F. Lauzier, S. English, L. McIntyre, J. Lacroix, D. Griesdale, P. Lessard-Bonaventure, A. F. TurgeonP347 - Hemoglobin thresholds and red blood cell transfusions in adult patients with moderate or severe traumatic brain injury: a retrospective cohort studyA. Boutin, L. Moore, R. Green, P. Lessard-Bonaventure, M. Erdogan, M. Butler, F. Lauzier, M. Chasse, S. English, L. McIntyre, R. Zarychanski, J. Lacroix, D. Griesdale, P. Desjardins, D. A. Fergusson, A. F. TurgeonP348 - Characteristics of patients with gunshot wounds to the head - an observational Brazilian studyB. Goncalves, B. Vidal, C. Valdez, A. C. Rodrigues, L. Miguez, G. MoralezP349 - Base excess as predictor for ICU admission and the injury severity in blunt trauma patientsT. HongP350 - Enhancement of usual emergency department care with proadrenomedullin to improve outcome prediction - Results from the multi-national, prospective, observational TRIAGE studyA. Kutz, P. Hausfater, D. Amin, T. Struja, S. Haubitz, A. Huber, B. Mueller, P. SchuetzP351 - Developing an innovative emergency medicine point-of-care simulation programmeT. Brown, J. Collinson, C. Pritchett, T. SladeP352 - The InSim program: an in situ simulation program for junior trainees in intensive careM. Le Guen, S. Hellings, R. RamsaranP353 - Impact of excessive and inappropriate troponin testing in the emergency setting how good are weA. AlsheikhlyP354 - The development of time tracking monitor at emergency departmentT. AbeP355 - Role of focussed echocardiography in emergency assessment of syncopeL. Kanapeckaite, M. Abu-Habsa, R. BahlP356 - Insertion of an open-ended 14-gauge catheter through the chest wall causes a significant pneumothorax in a self-ventilating swine modelM. Q Russell, K. J. Real, M. Abu-Habsa , R. M. Lyon, N. P. OvelandP357 - Ez-io® intraosseous access teaching in the workplace using a mobile ‘tea trolley’ training methodJ. Penketh, M. Mcdonald, F. KellyP358 - Black widow envenomation in Saudi Arabia: a prospective observational case seriesM. Alfafi, S. Alsolamy, W. Almutairi, B. AlotaibiP359 - Mechanical ventilation in patients with overdose not yet intubated on icu admissionA. E. Van den Berg, Y. Schriel, L. Dawson, I. A. MeynaarP360 - Central nervous system depressants poisoning and ventilator associated pneumonia: an underrated risk factor in toxicological intensive care unitH. TalaieP361 - Acute barium intoxication treated with hemodiafiltrationD. Silva, S. Fernandes, J. Gouveia, J. Santos SilvaP362 - Major trauma presenting to the emergency department. the spectrum of cycling injuries in IrelandJ. Foley, A. Kaskovagheorgescu, D. Evoy, J. Cronin, J. RyanP363 - Burns from French military operations: a 14-year retrospective observational analysis.M. Huck, C. Hoffmann, J. Renner, P. Laitselart, N. Donat, A. Cirodde, J. V. Schaal, Y. Masson, A. Nau, T. LeclercP364 - A comparison of mortality scores in burns patients on the intensive care unit.O. Howarth, K. Davenport, P. Jeanrenaud, S. RafteryP365 - Clasification of pain and its treatment and an intensive care rehabiliation clinicP. MacTavish, H. Devine, J. McPeake, M. Daniel, J. Kinsella, T. QuasimP366 - Pain management adequacy in critical care areas ,the process and the barriers perceived by critical care nursesS. Alrabiee, A. Alrashid , S. AlsolamyP367 - Pain assessment in critically ill adult patients: validation of the Turkish version of the critical-care pain observation toolO. Gundogan, C. Bor, E. Akýn Korhan, K. Demirag , M. UyarP368 - An audit of pain and sedation assessments in the intensive care unit: recommendations for clinical practiceF. Frame, C. Ashton, L. Bergstrom NiskaP369 - Impact of pharmaceutical care on treatment of pain and agitation in medical intensive care unitP. Dilokpattanamongkol, T. Suansanae, C. Suthisisang, S. Morakul, C. Karnjanarachata, V. TangsujaritvijitP370 - Agitation in trauma ICU, prevention and outcomeS. Mahmood, H. Al Thani, A. AlmenyarP371 Correlation between percentages of ventilated patients developed vap and use of sedative agents in icu patients.A. Vakalos , V. AvramidisP372 - Improving recording of sedation events in the Emergency Department: The implementation of the SIVA International Taskforce adverse event reporting tool for procedural sedationR. Sharvill, J. PenkethP373 - Impact of sedative drug use on the length of mechanical ventilationS. E. Morton, Y. S. Chiew, C. Pretty, J. G. Chase, G. M. ShawP374 - Co-administration of nitric oxide and sevoflurane using anacondaR. Knafelj, P. KordisP375 - A retrospective study of the use of Dexmedetomidine in an oncological critical care settingS. Patel, V. GroverP376 - Dexmedetomidine and posttraumatic stress disorder incidence in alcohol withdrawal icu patientsI. Kuchyn, K. BielkaP377 - Hemodynamic effects of dexmedetomidine in a porcine model of septic shockZ. Aidoni, V. Grosomanidis, K. Kotzampassi, G. Stavrou, B. Fyntanidou, S. Patsatzakis, C. SkourtisP378 - Ketamine for analgosedation in severe hypoxic respiratory failureS. D. Lee, K. Williams, I. D. WeltesP379 - Madness from the moon? lunar cycle and the incidence of delirium on the intensive care unitS. Berhane, C. Arrowsmith, C. Peters, S. RobertP380 - Impaired dynamic cerebral autoregulation after coronary artery bypass grafting and association with postoperative deliriumJ. Caldas, R. B. Panerai, T. G. Robinson, L. Camara, G. Ferreira, E. Borg-Seng-Shu, M. De Lima Oliveira, N. C. Mian, L. Santos, R. Nogueira, S. P. Zeferino, M. Jacobsen Teixeira, F. Galas, L. A. HajjarP381 - Risk factors predicting prolonged intensive care unit length of stay after major elective surgery.P. Killeen, M. McPhail, W. Bernal, J. Maggs, J. Wendon, T. HughesP382 - Systemic inflammatory response syndrome criteria and hospital mortality prediction in a brazilian cohort of critically ill patientsL. U. Taniguchi, E. M. Siqueira, J. M. Vieira Jr, L. C. AzevedoP383 - Evaluating the efficacy of a risk predictor panel in identifying patients at elevated risk of morbidity following emergency admissionA. N. Ahmad, M. Abu-Habsa, R. Bahl, E. Helme, S. Hadfield, R. LoveridgeP384 - A retrospective comparison of outcomes for elective surgical patients admitted post-operatively to the critical care unit or general wardJ. Shak, C. Senver, R. Howard-GriffinP385 - Effect of obesity on mortality in surgical critically ill patients.P. Wacharasint, P. Fuengfoo, N. Sukcharoen, R. RangsinP386 - The national early warning score (news) reliably improves adverse clinical outcome prediction in community-acquired pneumonia - results from a 6 year follow-upD. Sbiti-Rohr, P. SchuetzP387 - Clinical usefulness of the charlson¡¯s weighted index of comorbidities _as prognostic factor in patients with prolonged acute mechanical ventilationH. Na, S. Song, S. Lee, E. Jeong, K. LeeP388 - Comparison of mortality prediction scoring systems in patients with cirrhosis admitted to general intensive care unitM. Cooper, K. Milinis, G. Williams, E. McCarron, S. Simants, I. Patanwala, I. D. WeltersP389 - Impact of admission source and time of admission on outcome of pediatric intensive care patients: retrospective 15 years studyE. Zoumpelouli, EA Volakli, V. Chrysohoidou, S. Georgiou, K. Charisopoulou, E. Kotzapanagiotou, V. Panagiotidou, K. Manavidou, Z. Stathi, M. SdougkaP390 - Heart rate variability and outcomes prediction in critical illnessN. Salahuddin, B. AlGhamdi, Q. Marashly, K. Zaza, M. Sharshir, M. Khurshid, Z. Ali, M. Malgapo, M. Jamil, A. Shafquat, M. Shoukri, M. HijaziP391 - The incidence and outcome of hyperlactatemia in the post anaesthesia care unitT. Abe, S. Uchino, M. TakinamiP392 - Correlation between arterial blood gas disturbances and arterial lactate levels during hospitalization and outcome in critically septic patientsN. R. Rangel Neto, S. Oliveira, F. Q. Reis, F. A. RochaP393 - External validation of saps 3 and mpm iii scores in 48,816 patients from 72 brazilian icusG. Moralez, K. Ebecken, L. S. Rabello, M. F. Lima, R. Hatum, F. V. De Marco, A. Alves, J. E. Pinto, M. Godoy, P. E. Brasil, F. A. Bozza, J. I. Salluh, M. SoaresP394 - The frailty penalty: pre-admission functional status confounds mortality prediction models in critically ill patientsJ. Krinsley, G. KangP395 - ‘sooner rather than later”: how delayed discharge from critical care leads to increased out of hours discharges and subsequent increase in in-hospital mortality.J. Perry, H. HinesP396 - Identifying poor outcome patient groups in a resource-constrained critical care unitK. M. Wilkinson, C. Tordoff, B. Sloan, M. C. BellamyP397 - Effects of icu weekend admission and discharge on mortality.E. Moreira, F. Verga, M. Barbato, G. BurghiP398 - Organizational factors, outcomes and resource use in 9,946 cancer patients admitted to 70 ICUsM Soares, U. V. Silva, L. C. Azevedo, A. P. Torelly, J. M. Kahn, D. C. Angus, M. F. Knibel, P. E. Brasil, F. A. Bozza, J. I. SalluhP399 - Evaluation of oncological critically ill patients, severity score and outcome compared to not oncological in a particular hospital cti.M. B. Velasco, D. M. DalcomuneP400 - Outcomes of patients admitted to a large uk critical care department with palliative oncological diagnosesR. Marshall, T. Gilpin, A. Tridente, A. RaithathaP401 - Predictors of mortality in febrile neutropenic patients with haematological malignancies admitted to an intensive care unit of a cancer centerD. Mota, B. Loureiro, J. Dias, O. Afonso, F. Coelho, A. Martins, F. FariaP402 - Patients with hematologic malignancies requiring invasive mechanical ventilation: characteristics and predictors of mortalityH. Al-Dorzi, H. Al Orainni , F. AlEid, H. Tlaygeh, A. Itani, A. Hejazi, Y. ArabiP403 - Patient-important outcomes in randomized controlled trials in critically ill patients: a systematic reviewS. Gaudry, J. Messika, J. D. Ricard, S. Guillo, B. Pasquet, E. Dubief, D. Dreyfuss, F. TubachP404 - Alopecia in survivors of critical illness: a qualitative studyC . Battle, K. James, P. TemblettP405 - The impact of mental health on icu admissionL. Davies, C. Battle, C. LynchP406 - Cognitive impairment 5 years after ICU dischargeS. Pereira, S. Cavaco, J. Fernandes, I. Moreira, E. Almeida, F. Seabra Pereira, M. Malheiro, F. Cardoso, I. Aragão, T. CardosoP407 - Apache ii versus apache iv for octagenerians in medical icuM. Fister, R. KnafeljP408 - Outcomes of octagenarians in an indian icuP. Muraray Govind, N. Brahmananda Reddy, R. Pratheema, E. D. Arul, J. DevachandranP409 - Mortality and outcomes in elderly patients 80 years of age or older admitted to the icuM. B. Velasco , D. M. DalcomuneP410 - Octagenerians in medical icu - adding days to life or life to days?R. Knafelj, M. FisterP411 - The very elderly admitted to intensive care unit: outcomes and economic evaluationN. Chin-Yee, G. D’Egidio, K. Thavorn, D. Heyland, K. KyeremantengP412 - The very elderly in intensive care: relationship between acuity of illness and long-term mortalityA. G. Murchison, K. Swalwell, J. Mandeville, D. StottP413 - Acquired weakness in an oncological intensive care unitI. GuerreiroP414 - Musculoskeletal problems in intensive care unit (ICU) patients post-dischargeH. Devine, P. MacTavish, J. McPeake, T. Quasim, J. Kinsella, M. DanielP415 - Premorbid obesity, but not nutrition, prevents critical illness-induced muscle wasting and weaknessC. Goossens M. B. Marques, S. Derde, S. Vander Perre, T. Dufour, S. E. Thiessen, F. Güiza, T. Janssens, G. Hermans, I. Vanhorebeek, K. De Bock, G. Van den Berghe, L. LangoucheP416 - Physical outcome measures for critical care patients following intensive care unit (icu) dischargeH. Devine, P. MacTavish, T. Quasim, J. Kinsella, M. Daniel, J. McPeakeP417 - Improving active mobilisation in a general intensive care unitB. Miles , S. Madden, H. DevineP418 - Mobilization in patients on vasoactive drugs use – a pilot study.M. Weiler, P. Marques, C. Rodrigues, M. Boeira, K. Brenner, C. Leães, A. Machado, R. Townsend, J. AndradeP419 - Pharmacy intervention at an intensive care rehabilitation clinicP. MacTavish, J. McPeake, H. Devine, J. Kinsella, M. Daniel, R. Kishore, C. Fenlon, T. QuasimP420 - Interactive gaming is feasible and potentially increases icu patients’ motivation to be engaged in rehabilitation programsT. Fiks, A. Ruijter, M. Te Raa, P. SpronkP421 - Simulation-based design of a robust stopping rule to ensure patient safetyY. S. Chiew, P. Docherty, J. Dickson, E. Moltchanova, C. Scarrot, C. Pretty, G. M. Shaw, J. G. ChaseP422 - Are daily blood tests on the intensive care unit necessary?T. Hall, W. C. Ngu, J. M. Jack, P. MorganP423 - Measuring urine output in ward patients: is it helpful?B. Avard, A. Pavli, X. GeeP424 - The incidence of pressure ulcers in an adult mixed intensive care unit in turkeyC . Bor, E. Akin Korhan, K. Demirag, M. UyarP425 - Intensivist/patient ratios in closed ICUs in Alexandria, Egypt; an overviewM. Shirazy, A. FayedP426 - Eicu (electronic intensive care unit): impact on ALOS (average length of stay) in a developing country like IndiaS. Gupta, A. Kaushal, S. Dewan, A. VarmaP427 - Predicting deterioration in general ward using early deterioration indicatorE. Ghosh, L. Yang, L. Eshelman, B. Lord, E. CarlsonP428 - High impact enhanced critical care outreach - the imobile service: making a differenceE. Helme, R. Broderick, S. Hadfield, R. LoveridgeP429 - Impact of bed availability and cognitive load on intensive care unit (ICU) bed allocation: a vignette-based trialJ. Ramos, D. ForteP430 - Characteristics of critically ill patients admitted through the emergency departmentF. Yang, P. HouP431 - Admission to critical care: the quantification of functional reserveJ. Dudziak, J. Feeney, K. Wilkinson, K. Bauchmuller, K. Shuker, M. Faulds, A. Raithatha, D. Bryden, L. England, N. Bolton, A. TridenteP432 - Admission to critical care: the importance of frailtyK. Bauchmuller, K Shuker, A Tridente, M Faulds, A Matheson, J. Gaynor, D Bryden, S South Yorkshire Hospitals Research CollaborationP433 - Development of an instrument to aid triage decisions for intensive care unit admissionJ. Ramos, B. Peroni, R. Daglius-Dias, L. Miranda, C. Cohen, C. Carvalho, I . Velasco, D. ForteP434 - Using selective serotonin re-uptake inhibitors and serotonin-norepinephrine re-uptake inhibitors in critical care: a systematic review of the evidence for benefit or harmJ. M. Kelly, A. Neill, G. Rubenfeld, N. Masson, A. MinP435 - Measuring adaptive coping of hospitalized patients with a severe medical condition:the sickness insight in coping questionnaire (sicq)E. Boezeman, J. Hofhuis , A. Hovingh, R. De Vries, P. SpronkP436 - Results of a national survey regarding intensive care medicine trainingG. Cabral-Campello, I. Aragão, T. CardosoP437 - Work engagement among healthcare professionals in the intensive care unitM. Van Mol, M. Nijkamp, E . KompanjeP438 - Empowering the intensive care practitioners. is it a burnout ameliorating intervention?P. Ostrowski, A. OmarP439 - Icu patients suffer from circadian rhythm desynchronisationK. Kiss , B. Köves, V. Csernus, Z. MolnárP440 - Noise reduction in the ICU: feasible ?Y. Hoydonckx, S. Vanwing, B. Stessel, A. Van Assche, L. Jamaer, J. DuboisP441 - Accidental removal of invasive devices in the critical patient into the bed-washing. does the presence of professional nurse modify his incidence?V. Medo, R. Galvez, J. P. MirandaP442 - Deprivation of liberty safeguards (dols): audit of compliance in a of a 16-bed specialist cancer critical care unit.C. Stone, T. WigmoreP443 - Use of a modified cristal score to predict futility of critical care in the elderlyY. Arunan, A. Wheeler, K. Bauchmuller, D. BrydenP444 - Improvement of Referral Rate to Palliative Care for Patients with Poor Prognosis in Neurosurgical Intensive Care UnitY. Wong, C. Poi, C. GuP445 - Factors associated with limitation of life supporting care (lsc) in a medico-surgical intermediate care unit, and outcome of patients with lsc limitation: a monocentric, six-month study.P. Molmy, N. Van Grunderbeeck, O. Nigeon, M. Lemyze, D. Thevenin, J. MallatP446 - Palliative care consultation and intensive care unit admission request: a cohort studyJ. Ramos, M. Correa, R. T. Carvalho, D. ForteP447 - Nursing and medicine together in postsurgical intensive care unit: situations of prognostic conflict at the end of life. our critical care nurses suffer with our medical activism?A. Fernandez, C. McBrideP448 - End of life who may decideE. Koonthalloor, C. WalshP449 - Correctly diagnosing deathA. Webber, M. Ashe, K. Smith, P. JeanrenaudP450 - Skin procurement performed by intensive care physicians: yes, we can.A. Marudi , S. Baroni, F. Ragusa, E. BertelliniP451 - Death analysis in pediatric intensive care patientsE. A. Volakli , E. Chochliourou, M. Dimitriadou, A. Violaki, P. Mantzafleri, E. Samkinidou, O. Vrani, A. Arbouti, T. Varsami, M. SdougkaP452 - The potential impact of euthanasia on organ donation: analysis of data from belgiumJ. A. Bollen, T. C. Van Smaalen, W. C. De Jongh, M. M. Ten Hoopen, D. Ysebaert, L. W. Van Heurn, W. N. Van MookP453 - Communication within an intensive care settingK. Sim, A. FullerP454 - Development and implementation of a longitudinal communication curriculum for critical care medicine fellowsA. Roze des Ordons, P. Couillard, C. DoigP455 - Staff-family conflict in a multi-ethnic intensive care unitR. V. Van Keer, R. D. Deschepper, A. F. Francke, L. H. Huyghens, J. B. BilsenP456 - Does the source of admission to critical care affect family satisfaction?B. Nyamaizi, C. Dalrymple, A. Molokhia, A. DobruP457 - A simple alternative to the family satisfaction survey (fs-icu)E. Marrinan, A. Ankuli, A. MolokhiaP458 - A study to explore the experiences of patient and family volunteers in a critical care environment: a phenomenological analysisJ. McPeake, R. Struthers, R. Crawford , H. Devine , P. Mactavish , T. QuasimP459 - Prevalence and risk factors of anxiety and depression in relatives of burn patients.P. Morelli, M. Degiovanangelo, F. Lemos, V. MArtinez, F. Verga, J. Cabrera, G. BurghiP460 - Guidance of visiting children at an adult intensive care unit (icu)A. Rutten , S. Van Ieperen, S. De Geer, M. Van Vugt, E. Der KinderenP461 - Visiting policies in Italian pediatric ICUs: an updateA. Giannini, G Miccinesi, T Marchesi, E Prandi
Highlights
A hallmark of sepsis is early onset microvascular dysfunction
This loss of local microvascular control was partially off-set by increased capillary red blood cell (RBC) supply rate, which correlated with increased plasma NOx
The similarities in the phenotype induced by sepsis and suppression of A1R support our hypothesis that dysfunction/downregulation of the Gi-A1R at the onset of sepsis changes the effect of adenosine towards Gs-A2AR/A2BR-mediated leukopenia and immune paralysis
Summary
A hallmark of sepsis is early onset microvascular dysfunction. the mechanism responsible for maldistribution of capillary blood flow is not understood. Methods: We studied 212 patients [survival (S) group: 146; nonsurvival (NS) group: 66] in whom PMX-DHP was performed for severe sepsis and septic shock and who were admitted to the ICU. Methods: Histone H3 (H3) plasma levels of 43 sepsis patients who were admitted to the Intensive Care Unit were measured and we determined the correlation of H3 levels with disease severity, organ failure, mortality and coagulation- and tissue homeostasis parameters including LDH levels, thrombin potential (ETP), prothrombin levels, antithrombin levels and platelet counts. Results: For sepsis patients at the ICU we found that median H3 levels were significantly increased in non-survivors as compared to survivors with levels found being 3.15 μ g/ml versus 0.57 μg/ml respectively, P = 0.04. Our survey could contribute towards liberalizing visiting policies in Italian PICUs and promoting more attentive care for the patient and his/her family
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
