Abstract

目的 探讨MgS04治疗前置胎盘所致的妊娠晚期阴道出血的效果与安全性.方法 102例前置胎盘患者作为治疗组,30 min内静脉输入MgSO4负荷量4g,随后以1.5 g·/h1维持,宫缩消失及阴道流血停止12h后停药.如复发,从负荷量开始重复治疗,但每天不应超过30g.同期条件相同38例前置胎盘患者为对照组,肌肉注射鲁米那0.2~0.3g,每4~6h1次.结果治疗组有效99例(97.1%),对照组有效14例(36.8%),两组差异有显著性(P<0.01);治疗组在止血、推迟分娩时间明显优于对照组,差异有显著性(P<0.05);治疗组新生儿死亡1例(0.98%),对照组新生儿死亡5例(13.16%),治疗组明显低于对照组.结论 MgS04治疗前置胎盘疗效显著,应用安全,可作为首选药物。

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