Abstract

Objective To compare the efficacy of ritodrine hydrochloride and magnesium sulfate in the treatment of placenta previa and their effects on maternal and infant outcomes. Method s 80 patients with placenta previa admitted to our hospital from May 2018 to March 2019 were selected, and were divide into observation group (n=40) and control group (n=40) with the random red and green lottery method. The control group was treated with magnesium sulfate, while the observation group was treated with ritodrine hydrochloride. The maternal clinical indicators (vaginal hemostasis time, vaginal bleeding volume, prolonged gestational weeks, vaginal hemostasis rate), neonatal clinical indicators (success rate of fetal protection, vaginal spontaneous delivery rate, Apgar score, and body weight), and drug safety were compared between the two groups. Result s The prolongation of gestational weeks, the rate of vaginal hemostasis, the success rate of fetal protection, the rate of vaginal spontaneous delivery, the Apgar score of newborns, and the body weight of newborns in the observation group were higher than those in the control group, and there were statistically significant differences between the two groups (P<0.05). The time of vaginal hemostasis and the amount of vaginal bleeding in the observation group were lower than those in the control group, with statistically significant differences (P<0.05). The incidence of adverse reactions was 7.5% (3/40) in the observation group and 22.5% (9/40) in the control group, there was statistically significant difference between the two groups (P<0.05). Conclusion In the clinical treatment of placenta previa, ritodrine hydrochloride is superior to magnesium sulfate, which can effectively improve the maternal and neonatal indicators, and has high safety, which is worthy of promotion. Key words: Placenta previa; Ritodrine hydrochloride; Magnesium sulfate; Maternal and infant outcomes

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