Abstract
Once-daily application of tretinoin to photodamaged facial skin for 0-12 months results in substantial clinical and histologic improvement. As regards appearance, fine wrinkles become effaced, dyspigmentations fade, surface becomes smooth and develops a 'rosy glow'. Histologically, atrophy and dysplasia of the epidermis are completely corrected. New collagen is laid down subepidermally along with the development of new small vessels (angiogenesis). Mesenchymal dermal cells become more numerous and larger. The sum of changes is toward more youthful skin.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Skin pharmacology : the official journal of the Skin Pharmacology Society
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
