Abstract
To our knowledge, we report the first case of 43-year-old female patient with recalcitrant pemphigoid vegetans successfully treated with a combination of the selective Janus kinase 1 inhibitor abrocitinib and oral corticosteroids. After abrocitinib therapy at a dose of 100 mg per day, the itching relieved significantly within 24 h. Three months later the bullous pemphigoid disease area index decreased to 9, and both the anti-BP230 and anti-BP180 antibody levels decreased. Then the dose of prednisone tapered to 20 mg daily and abrocitinib discontinued without a relapse during follow-up.
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