Abstract
The Journal of Cancer Metastasis and Treatment is an open access journal focused on cancer metastasis and treatment, including the occurrence, development, progression, metastasis, and treatment of oncologic disease. It covers basic, translational and clinical research related to cancer cell biology, genomics, precision medicine, oncology internal medicine, radiotherapy and radiology, obstetrics and gynecology, pediatrics, surgery, hematology, neurooncology, etc.
Highlights
Antonio SommarivaSurgical Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, 35128 Padova, Italy. How to cite this article: Sommariva A. Treatment of liver metastases in patients selected for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal carcinomatosis. J Cancer Metastasis Treat 2017;3:362-7. Article history: Received: 25 May 2017 First Decision: Sep 2017 Revised: 9 Oct 2017 Accepted: Oct 2017 Published: Dec 2017 Key words: Colorectal cancer, peritoneal carcinomatosis, liver metastases, hyperthermic intraperitoneal chemotherapy, liver resection
Peritoneal carcinomatosis (PC) from colorectal carcinoma is present in about 10% of patients at the time of diagnosis, and appears in 25% of patients during follow-up[ . 1,2] Median survival of patients affected by colorectal peritoneal carcinomatosis varies between 5 and 7 months[3]
In retrospective studies investigating the role of cytoreductive surgery (CS) + hyperthermic intraperitoneal chemotherapy (HIPEC) + liver resection (LR), the procedure resulted in a median survival between 15 and 23 months, a little worse with respect to the one reported for CS + HIPEC alone[20, . 29-32] in a comparative retrospective analysis of single centers, the 2-year overall survival seems lower when liver metastases are treated at the time of CS + HIPEC, ranging 43.3-89.5% for CS + HIPEC alone, and 26.8-70.2% for CS + HIPEC combined with LR[30,31,32] [Table 2]
Summary
Surgical Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, 35128 Padova, Italy. How to cite this article: Sommariva A. Treatment of liver metastases in patients selected for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal carcinomatosis. J Cancer Metastasis Treat 2017;3:362-7. Article history: Received: 25 May 2017 First Decision: Sep 2017 Revised: 9 Oct 2017 Accepted: Oct 2017 Published: Dec 2017 Key words: Colorectal cancer, peritoneal carcinomatosis, liver metastases, hyperthermic intraperitoneal chemotherapy, liver resection
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