Abstract
Mucormycosis is caused by zygomycetes. This fungus can cause a variety of infections in human beings, particularly in the immunocompromised patients. Zygomycetes impinge into the vascular network, resulting in thrombosis and necrosis of the surrounding tissues. Acute necrosis of maxilla is not frequently seen, and extensive facial bone involvement is rare in patients with oral mucormycosis. Sinus mucormycosis is often accompanied by a poor prognosis and a high mortality rate (46%). Therefore aggressive surgical intervention with antifungal therapy is usually necessary. In this report, we presented a case of rhino-orbital mucormycosis in a 60-year-old man with diabetes mellitus. Besides antifungal treatment, this patient also received several surgeries to remove all necrotic tissues, including the palate, maxilla, zygoma and orbital floor and lateral wall. Pre-bent titanium mesh on a 3D prototyping model and a temporalis muscle flap were used to do reconstruction and the results have been uneventful so far.
Published Version
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