TREATMENT OF ESOPHAGEAL ATRESIA IN GERMANY: ANALYSIS OF NATIONAL HOSPITAL DISCHARGE DATA FROM 2016 TO 2022

Abstract

BackgroundEsophageal atresia (EA) is a complex malformation. Multidisciplinary management is necessary, with the operative repair being the most challenging step in the treatment algorithm. The complete care structure for children with EA in Germany has not been analyzed yet. MethodsIn the observed period 2016-2022, inpatient EA cases were analyzed 1) during the hospital stay of birth, and 2) during the hospital stay of corrective surgery in patients aged up to 365 days, both based on national hospital discharge data. Patients’ comorbidities, hospital caseload, treatment characteristics (e.g. surgical approach) and outcome parameters were analyzed. Results1) 1,190 newborn EA cases were treated in 260 hospitals during the perinatal period. 54% had at least one additional malformation, and 16% had a birthweight below 1,500 grams. In-hospital mortality was 8.4%.2) 1,475 corrective operations for EA were performed in 111 hospitals with a consistent median annual caseload of 2 (P25-P95 1-8) per hospital. At least one indicator for a complicated perioperative course was documented in 63.7% of cases. The use of bronchoscopy was coded in 50% of cases. Median ventilation time during the entire hospital stay was 176 hours (P25-P95: 95-1759 hours). ConclusionsNewborns with EA are complex and early postoperative complications are common. The care structure is decentralized, and there was no trend towards centralization in the observed period. The low documented use of bronchoscopy is noteworthy. Centralization of the highly complex and schedulable corrective surgery for EA is necessary to evaluate outcomes and might improve the quality of care and resource utilization. Category of the manuscript and type of studyoriginal article, observational cross-sectional study, secondary data analysis